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Article Abstract
Summary: Single-cell DNA template strand sequencing (Strand-seq) enables chromosome length haplotype phasing, construction of phased assemblies, mapping sister-chromatid exchange events and structural variant discovery. The initial quality control of potentially thousands of single-cell libraries is still done manually by domain experts. ASHLEYS automates this tedious task, delivers near-expert performance and labels even large datasets in seconds.
Availability And Implementation: github.com/friendsofstrandseq/ashleys-qc, MIT license.
Supplementary Information: Supplementary data are available at Bioinformatics online.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504637 | PMC |
| http://dx.doi.org/10.1093/bioinformatics/btab221 | DOI Listing |
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