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http://dx.doi.org/10.1093/pm/pnaa478 | DOI Listing |
Pain Med Case Rep
August 2025
Pain Management Department, Hospital Zambrano Helión, Monterrey, Nuevo León, México.
Background: Harlequin syndrome (HS) is a rare clinical manifestation characterized by unilateral sweating and flushing of the face, neck, upper chest, and/or arm, which results from a dysfunction of the autonomic nervous system. Symptoms may worsen with heat, stress, strenuous exercise, or emotional reactions. The syndrome is also associated with traumatic or vascular injuries, tumors, or complications from medical procedures, such as radiofrequency ablation (RFA), surgery, intravenous cannulation, among others.
View Article and Find Full Text PDFCephalalgia
September 2025
NIHR King's Clinical Research Facility and SLaM Biomedical Research Centre, King's College, London, UK.
AimTo evaluate the effectiveness and tolerability of non-invasive vagus nerve stimulation (nVNS) as acute or preventive treatment, or both, in a cohort of trigeminal autonomic cephalalgia (TAC) patients.MethodsA service evaluation retrospectively included patients with TACs between January 2014 and February 2025 who had used, or currently use, nVNS. Data were collected from clinical letters.
View Article and Find Full Text PDFCephalalgia
September 2025
Université Clermont Auvergne, CHU Clermont-Ferrand, Neuro-Dol, Inserm, Clermont-Ferrand, France.
Transl Psychiatry
August 2025
German Center for Mental Health (DZPG), Partner Site Jena-Magdeburg-Halle, Jena-Magdeburg-Halle, Germany.
Depression is associated with reduced functional connectivity within the brain's salience network and its strengthened interactions with the default mode network (DMN). Modification of this clinical pattern is challenging. Leveraging the direct neural pathways from olfactory processing regions to the salience network, we explored the effects of electrical stimulation of the olfactory mucosa on brain connectivity.
View Article and Find Full Text PDFPrim Dent J
June 2025
Priya Thakrar BDS (Hons), FDS (OM) RCS Eng, PGCAPHE (KCL), FHEAConsultant in Oral Medicine, Royal National ENT and Eastman Dental Hospitals, London, UK.
Trigeminal neuralgia (TN) is a debilitating facial pain condition that can significantly impact a patient's quality of life. Typically, pain episodes are unpredictable lasting seconds to minutes, usually presenting in a unilateral distribution of the trigeminal nerve.Patients will often seek help from primary care dental practitioners during an acute attack, in need of pain relief and support in managing the pain.
View Article and Find Full Text PDF