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Grape pomace (GP) is a low-value by-product that contains a significant amount of high value-added products. The huge amount of non-edible residues of GP wastes (seeds, skins, leaves and, stems) produced by wine industries causes' environmental pollution, management issues as well as economic loss. Studies over the past 15-20 years revealed that GP could serve as a potential source for valuable bioactive compounds like antioxidants, bioactive, nutraceuticals, single-cell protein, and volatile organic compounds with an increasing scientific interest in their beneficial effects on human and animal health. However, the selection of appropriate techniques for the extraction of these compounds without compromising the stability of the extracted products is still a challenging task for the researcher. Based on the current scenario, the review mainly summarizes the novel applications of winery wastes in many sectors such as agriculture, pharmaceuticals, cosmetics, livestock fields, and also the bio-energy recovery system. We also summarize the existing information/knowledge on several green technologies for the recovery of value-added by-products. For the promotion of many emerging technologies, the entrepreneur should be aware of the opportunities/techniques for the development of high-quality value-added products. Thus, this review presents systematic information on value-added by-products that are used for societal benefits concerning the potential for human health and a sustainable environment.
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http://dx.doi.org/10.1016/j.envpol.2021.116796 | DOI Listing |
Foods
August 2025
College of Enology, Northwest A&F University, Yangling 712100, China.
With the development of people's diets and working patterns, obesity is an increasingly serious health threat faced globally. Grape pomace is an important by-product generated during the wine production process which is rich in polyphenols. Polyphenols show promising potential in anti-inflammatory, antioxidant, and metabolic regulatory applications.
View Article and Find Full Text PDFInt J Mol Sci
August 2025
Centro de Excelencia en Nanotecnología Leitat Chile, Fundación Leitat Chile, Román Díaz 532, Providencia, Santiago 8380000, Chile.
Grape pomace is a major by-product of winemaking and a rich source of phenolic compounds with antioxidant potential. The Carménère variety, emblematic of Chilean viticulture, remains underutilized despite its high anthocyanin and flavanol content. This study aimed to develop a cost-effective method to recover and stabilize bioactive compounds from Carménère grape pomace.
View Article and Find Full Text PDFAnimals (Basel)
August 2025
Centro de Investigación en Alimentación y Desarrollo, A.C. Carretera Gustavo Enrique Astiazarán Rosas, No. 46, Col. La Victoria, Hermosillo 83304, Sonora, Mexico.
Given the restrictions on animal growth promoters, alternative plant-based additives-particularly those rich in phenolic compounds, such as agro-industrial by-products-have been explored. These additives help to mitigate heat stress, which negatively affects productivity by impacting intestinal health and antioxidant status. This study evaluated the effects of individual and combined supplementation of ferulic acid (FA) and grape pomace (GP) on antioxidant enzyme activity, as well as intestinal histomorphometry, in finishing pigs under heat stress.
View Article and Find Full Text PDFNanomaterials (Basel)
August 2025
Centro de Excelencia en Materiales Avanzados-Nanotecnología, LEITAT Chile, Santiago 7500724, Chile.
In this study, a green hydrothermal synthesis method was employed to produce and /β-MnO nanostructures using EET-50, an organic extract obtained from a by-product of Carménère wine production. The biomolecules in EET-50 acted as reducing agents due to their electron-donating functional groups, enabling nanostructure formation without the need for additional chemical reductants. Morphological characterization by SEM revealed that a KMnO/EET-50 mass ratio of 3:1 led to the synthesis of nano-octahedra alongside rod-like structures, with shorter reaction times favoring the development of isolated nano-octahedra ranging from 100 nm to 170 nm.
View Article and Find Full Text PDFFront Nutr
August 2025
Farmacognosia, FBioyF, UNR y CONICET, Rosario, Argentina.
Grape pomace, a by-product of winemaking, has emerged as a promising source of natural antimicrobial compounds for food applications. In response to increasing concerns regarding foodborne illnesses and consumer demand for clean-label products, its valorization represents a sustainable approach to enhance food safety and shelf life. This review combines a bibliometric analysis with a critical examination of the scientific literature.
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