Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Download full-text PDF

Source
http://dx.doi.org/10.1111/trf.16357DOI Listing

Publication Analysis

Top Keywords

pair s-silencing
4
s-silencing single
4
single nucleotide
4
nucleotide variants
4
variants cis-linked
4
cis-linked gypb
4
pair
1
single
1
nucleotide
1
variants
1

Similar Publications

Antigenic variation in the human malaria parasite Plasmodium falciparum depends on the transcriptional regulation of the var gene family. In each individual parasite, mRNA is expressed exclusively from 1 var gene out of ∼60, while the rest of the genes are transcriptionally silenced. Both modifications to chromatin structure and DNA regulatory elements associated with each var gene have been implicated in the organization and maintenance of the silent state.

View Article and Find Full Text PDF