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The emergence and spread of vector-borne diseases (VBDs) is a function of biotic, abiotic and socio-economic drivers of disease while their economic and societal burden depends upon a number of time-varying factors. This work is concerned with the development of an early warning system that can act as a predictive tool for public health preparedness and response. We employ a host-vector model that combines entomological (mosquito data), social (immigration rate, demographic data), environmental (temperature) and geographical data (risk areas). The output consists of appropriate maps depicting suitable risk measures such as the basic reproduction number, , and the probability of getting infected by the disease. These tools consist of the backbone of a semi-automatic early warning system tool which can potentially aid the monitoring and control of VBDs in different settings. In addition, it can be used for optimizing the cost-effectiveness of distinct control measures and the integration of open geospatial and climatological data. The R code used to generate the risk indicators and the corresponding spatial maps along with the data is made available.
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http://dx.doi.org/10.3390/ijerph18041823 | DOI Listing |
Food Chem
September 2025
Wuxi Haihe Equipment Scientific & Technological Co., Wuxi, China.
To study the impact of pH-responsive labels prepared using traditional and different printing methods on fruit freshness monitoring and preservation, this study firstly optimized coaxial 3D printed labels by analyzing core-shell ratios and infill ratios, and predicted the impact of printing design on functionality of labels via four models. Then, the physicochemical properties of cast, dual-nozzle 3D printed, and coaxial 3D printed labels were compared. Finally, lightweight deep convolutional neural network models were used to enhance early warning intelligence.
View Article and Find Full Text PDFFront Microbiol
August 2025
Shanghai Kangshi Food Science and Technology Co., Ltd., Shanghai, China.
Unlabelled: Spices play a ubiquitous role in the food industry, imparting distinctive flavors and exhibiting antibacterial properties. Nonetheless, microbial contamination and residues present persistent challenges to food safety within this sector. The systematic tracking of microbial input datasets in spices holds significant guiding implications and economic value for microbial control and risk assessment in the food industry.
View Article and Find Full Text PDFFront Microbiol
August 2025
College of Life Sciences, Hebei University, Baoding, China.
Introduction: The Zika virus (ZIKV) envelope (E) protein is critical for viral replication and host interactions. Although glycosylation of the E protein is known to influence viral infectivity and immune evasion, the specific functional roles of E protein glycosylation in ZIKV infectivity in mosquito cells remain unclear.
Methods: In this study, we generated a deglycosylation mutant ZIKV with a T156I substitution in the E protein and investigated its effects on viral replication and viral-host interactions in mosquito C6/36 cells.
Front Public Health
September 2025
Department of Environmental Health, Harvard T. H. Chan School of Public Health, Boston, MA, United States.
The frequency and severity of heat waves are expected to worsen with climate change. Exposure to extreme heat, or prolonged unusually high temperatures, are associated with increased morbidity and mortality. The fetus, infant, and young child are more sensitive to higher temperatures than older children and most adults given that they are rapidly developing.
View Article and Find Full Text PDFFront Cardiovasc Med
August 2025
Department of Emergency, The First People's Hospital of Guiyang, Guiyang, China.
Objective: Sepsis is a common and life-threatening syndrome in intensive care units, frequently accompanied by myocardial dysfunction, which significantly worsens patient outcomes. S100A12, a calcium-binding protein associated with inflammation, is upregulated in various inflammatory conditions. However, its role in sepsis and related cardiac injury remains unclear.
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