Ex Vivo Complement Activation on Endothelial Cells: Research and Translational Value.

Trends Mol Med

Centre de Recherche des Cordeliers, INSERM, Sorbonne Université, Université de Paris, F-75006 Paris, France. Electronic address:

Published: May 2021


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Article Abstract

The spectrum of human diseases with complement contribution is ever increasing. Tools to study the complement contribution and the potential interest of novel complement inhibitors in clinical practice are lacking. Here we discuss a functional ex vivo assay to monitor complement activation on endothelial cells, which can answer to this need.

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http://dx.doi.org/10.1016/j.molmed.2021.01.008DOI Listing

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