Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
This study increases our understanding of how diet-driven phenotypic plasticity can help non-target aquatic invertebrates deal with chlorpyrifos (CPO) exposure. A bioassay was performed over 6 days with the freshwater shrimp Macrobrachium borellii. Experimental treatments included CPO-treated shrimps (10 μg L) were fed with (i) a lipid-rich diet, (ii) a lipid-medium diet, or (iii) a lipid-poor diet. Control shrimps (no CPO exposure) received the same diets as detailed above. Cholinesterases and carboxylesterases were determined as an indicator of CPO exposure. Results showed that diets with a medium-to-high lipid content were important inducers of esterase activity, while shrimps exposed to CPO under a lipid-poor diet showed a significant enzymatic inhibition. This diet-dependent esterase induction suggests that the intake of fatty dietary items mitigates the esterase enzyme inhibition caused by CPO exposure.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s11356-021-13055-w | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Immune-sparing potential of isocentric lateral decubitus positioning in adjuvant whole-breast radiotherapy.
Strahlenther Onkol
July 2025
Proton Therapy Center (CPO), Institut Curie, Orsay, France.
Background: Lymphocytes are among the most radiosensitive cell types, and low-dose exposure during radiotherapy has been associated with measurable immune suppression. In breast cancer treatment, systemic immune exposure is partly driven by irradiation of highly vascularized organs such as the heart, lungs, and liver. The axillary lymph nodes also play a critical role in initiating antitumor immune responses.
View Article and Find Full Text PDFProton therapy in young breast cancer patients with germline TP53 and ATM mutations: a case series.
Strahlenther Onkol
May 2025
Department of radiation oncology, Institut Curie, Paris, France.
Background: Young breast cancer patients with germline radiosensitivity mutations, such as in TP53 and ATM, face an increased risk of radiation-induced toxicities and secondary malignancies. Proton therapy offers dosimetric advantages by reducing the radiation exposure of healthy tissues, potentially mitigating these risks. However, clinical data on the use of proton therapy in this specific population are limited.
View Article and Find Full Text PDFChlorpyrifos-oxon results in autophagic flux dysfunction contributing to neuronal apoptosis via a ROS/AMPK/CHOP activation pathway.
Chem Biol Interact
May 2025
School of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung, 404, Taiwan; Department of Nursing, College of Medical and Health Science, Asia University, Taichung, 413, Taiwan. Electronic address:
Chlorpyrifos (CPF) is a widely used organophosphate (OP) pesticide in agriculture and sanitation, known to elicit neurotoxic effects. Chlorpyrifos-oxon (CPO), a metabolite of CPF, is the primary neurotoxic agent, yet its mechanisms are less understood. In this study, we investigated the effects and underlying mechanisms of CPO-induced neurotoxicity.
View Article and Find Full Text PDF[Risk apportionment to remote and recent asbestos exposures for pleural mesothelioma].
Epidemiol Prev
May 2025
Epidemiologia dei Tumori, Centro per la Prevenzione Oncologica del Piemonte (CPO-Piemonte) e Università di Torino, Torino.
Background: the exposure-response relationship between pleural mesothelioma and asbestos has been traditionally described by models that predicted incidence to increase indefinitely by latency. Studies with long observation showed that the increase flattens out beyond 40 years of latency. It has been, therefore, proposed to introduce an exponential decay function into the models Objectives: to show characteristics and implications as to the relevance of remote and recent exposures, by conducting a simulation exercise based on data available from the literature.
View Article and Find Full Text PDFExposure to climate change-related extreme events in the first year of life and occurrence of infant wheezing.
Environ Int
February 2025
Cancer Epidemiology Unit, Medical Science Department, University of Turin and CPO Piemonte, Via Santena 7, 10126, Turin, Italy; Barcelona Supercomputing Center (BSC), Barcelona, Spain.
Introduction: Climate change increases the intensity and frequency of extreme events, which will most impact younger generations. Within the NINFEA birth cohort, we investigated the relationship between exposure to such events during the first year of life and infant respiratory health.
Methods: The NINFEA cohort study recruited pregnant women across 11 years in Italy, allowing for climatic variability exploitation by birth place and time.