Multi-beam OCT imaging based on an integrated, free-space interferometer.

Biomed Opt Express

Wellman Center for Photomedicine, Massachusetts General Hospital, 40 Blossom St., Boston, MA 02114, USA.

Published: January 2021


Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

While it is a common practice to increase the speed of swept-source optical coherence tomography (OCT) systems by using a high-speed source, this approach may not always be optimal. Parallelization in the form of multiple imaging beams is an alternative approach, but scalable and low-loss multi-beam OCT architectures are needed to capitalize on its advantages. In this study, we demonstrate an eight-beam OCT system using an interferometer architecture comprising planar lightwave circuits (PLC) splitters, V-groove assemblies (VGA), and optical ribbon fibers. We achieved an excess loss and heterodyne efficiency on each channel that was close to that of single-beam systems. structural imaging of a human finger and OCT angiography imaging of a mouse ear was performed to demonstrate the imaging performance of the system. This work provides further evidence supporting multi-beam architectures as a viable strategy for increasing OCT imaging speed.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7818951PMC
http://dx.doi.org/10.1364/BOE.408703DOI Listing

Publication Analysis

Top Keywords

multi-beam oct
8
oct imaging
8
imaging
6
oct
5
imaging based
4
based integrated
4
integrated free-space
4
free-space interferometer
4
interferometer common
4
common practice
4

Similar Publications

Microscopes generally achieve better 2D imaging compared to 3D, and super-resolution microscopes often aggravate such axial-lateral resolution mismatch. A prime example is vortex phase-based stimulated emission depletion (STED) fluorescence microscopy, which only narrows the point-spread function laterally, thereby increasing the point-spread function (PSF) anisotropy. In this study, we developed a semi-analytical theory based on the Nijboer-Zernike expansion, developed a set of metrics and performed experiments to establish the merits of the alternative, bivortex phase-based, coherent-hybrid STED.

View Article and Find Full Text PDF
Article Synopsis
  • Multi-beam-pumped optical parametric amplification (OPA) aims to improve ultraintense femtosecond lasers but faces issues like low conversion efficiency and inter-channel crosstalk due to multi-idler-waves.
  • The paper proposes a new method called multi-beam-pumped quasi-parametric amplification (QPA) as a solution to these challenges.
  • Theoretical analysis shows that strong idler dissipation in two-beam-pumped QPA can effectively reduce crosstalk and diffraction, making it a promising approach for enhancing femtosecond laser pulses efficiently and robustly.
View Article and Find Full Text PDF

We report a method for generating uniform, artifact-free total internal reflection fluorescence (TIRF) excitation via a photonic lantern. Our tapered waveguide, consisting of a multimode input and nine few-mode outputs, enables single-shot TIRF illumination from nine azimuthal directions simultaneously without the introduction of nonstationary devices. Utilizing the photonic lantern for multi-beam excitation provides a low-loss mechanism that supports a wide range of light sources, including high-coherence lasers and various wavelengths in the visible spectrum.

View Article and Find Full Text PDF

Solid-state light-detection-and-ranging (LiDAR) sensors based on integrated optical phased arrays (OPAs) have shown significant promise to reduce the cost, size, weight, and power consumption associated with LiDAR for autonomous systems. However, these OPA-based LiDAR systems typically operate by rastering a single beam, generating point clouds that constitute a significant amount of data and computational burden in the process. In this paper, we develop and experimentally demonstrate a novel multi-beam solid-state OPA-based LiDAR system capable of detecting and ranging multiple targets simultaneously, passively, and without rastering.

View Article and Find Full Text PDF

Review of Photodetectors for Space Lidars.

Sensors (Basel)

October 2024

Planetary Geology, Geophysics and Geochemistry Laboratory, Solar System Exploration Division, NASA Goddard Space Flight Center, Greenbelt, MD 20771, USA.

Photodetectors play a critical role in space lidars designed for scientific investigations from orbit around planetary bodies. The detectors must be highly sensitive due to the long range of measurements and tight constraints on the size, weight, and power of the instrument. The detectors must also be space radiation tolerant over multi-year mission lifetimes with no significant performance degradation.

View Article and Find Full Text PDF