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Designing collective behaviors for robot swarms is a difficult endeavor due to their fully distributed, highly redundant, and ever-changing nature. To overcome the challenge, a few approaches have been proposed, which can be classified as manual, semi-automatic, or automatic design. This paper is intended to be the manifesto of the automatic off-line design for robot swarms. We define the off-line design problem and illustrate it via a possible practical realization, highlight the core research questions, raise a number of issues regarding the existing literature that is relevant to the automatic off-line design, and provide guidelines that we deem necessary for a healthy development of the domain and for ensuring its relevance to potential real-world applications.
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http://dx.doi.org/10.3389/frobt.2019.00059 | DOI Listing |
PLoS One
September 2025
Grupo GITA, Facultad de Minas, Universidad Nacional de Colombia, Medellín, Colombia.
The development of an impulsive automated insulin delivery system (i-AiDS) for type 1 diabetes mellitus aims to provide real-time blood glucose regulation with minimal human intervention. This study presents the validation of an offset-free impulsive zone model predictive control strategy designed to cope with external disturbances such as meal intake and plant-model mismatch in a diabetic rat model. Fourteen male Wistar rats induced diabetes with streptozotocin were monitored using an continuous glucose monitoring and regulated by delivering insulin with a customized low-cost pump.
View Article and Find Full Text PDFAppl Opt
February 2025
In response to the increasing competition and rapid advancements in the automotive industry, manufacturers have designed more intricate structures to circumvent patent disputes. However, this approach has simultaneously resulted in extended development cycles, increased manufacturing costs, and prolonged production times. Consequently, reducing development cycles and cutting costs have become key objectives for leading automobile manufacturers.
View Article and Find Full Text PDFTransfusion
August 2025
Department Cardio-Thoracic and Vascular Sciences, University of Padua, Padua, Italy.
Background: Several studies show that extracorporeal photopheresis (ECP) might benefit chronic lung allograft dysfunction (CLAD). A standard ECP cycle consists of two consecutive procedures regardless of the technique employed.
Study Design And Methods: Evaluation of ECP cycle (from two to one procedure) modification due to pandemic restrictions in 25 patients with CLAD under chronic treatment by off-line ECP in the 6 months preceding cycle modification (one procedure processing 1.
Mol Cell Proteomics
July 2025
Department of Biochemistry and Molecular Biology and the Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia. Electronic address:
Pancreatic ductal adenocarcinoma (PDAC), with its devastating prognosis and limited treatment options, demands innovative therapeutic strategies. T-cell-based immunotherapy has shown promise for many cancers, including PDAC, but is limited by our knowledge of the breadth of cancer-specific T-cell epitopes available. Thus, a comprehensive assessment of the immunopeptidome of PDAC is essential to pave the way for the effective design of immunotherapy and related interventions.
View Article and Find Full Text PDFJ Integr Neurosci
June 2025
Department of Human Movement Science, Incheon National University, 22012 Incheon, Republic of Korea.
Background: Aging can cause degenerative changes in motor and cognition-related brain areas, presumably by interfering with gait performance in healthy aging populations. We aimed to assess the effects of transcranial direct current stimulation (tDCS) on single- and dual-task walking performances in healthy older adults using meta-analytic approaches.
Methods: Eleven studies were qualified based on the inclusion criteria: (a) healthy older adults, (b) treatment = tDCS protocols, (c) control = sham stimulation, (d) gait performance outcomes, and (e) randomized controlled trials using parallel or crossover designs.