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Objective: Urinary pH is a factor that influences in urinary lithogenesis. It can condition the heterogeneous nucleation of calcium oxalate and the crystallization or dissolution of other substances such as uricacid, cystine and phosphates. Its exact and precise measurement is a tool to guide the treatment and prevention. The most accurate way to measure the pH is to use a glass electrode and a pH-meter, but this device is used in hospital's environment and is not portable. Test strips are not adequate for proper measurement. Recently, a portable and electronic device for measuring urinary pH has shown greater precision and accuracy in the measurement of urinary pH, with good acceptance by patients.
Method: We carried out a bibliographic search inPUBMED and EMBASE using the terms "URINARY pH", "Lithiasis", "Uro-Lihitiasis", "Urinary Stone", "Urinary pH measurement", in order to compile articles, books, abstracts and the most relevant clinical guides in English and Spanish on this topic.
Results: We select a total of 66 articles, 3 books, an abstract of a study unpublished presented at the American urology congress and the European Guidelines on urolithiasis on the effect of pH on the formation and prevention of urolithiasis. Four articles deal specifically with the effect of urinary pH on urolithiasis, 5 articles deal with a new portable electronic device for measuring urinary pH, 5 articles dealt with the measurement of urinary pH with test strips and 1 article dealt with the modification of urinary pH to reduce fouling of double J catheters, 2 articles deal about the urinary acidification with oral methionine. The selected abstract deals with the new portable device for measuring urinary pH in cystinuric patients. The 3 selected books have specific sections where the role of urinary pH in urolithiasis is discussed. Finally, in the European Urology Guidelines, the control of urinary pH is emphasized in the sections of prevention of urolithiasis formation, treatment of uric lithiasis, infectious/non-infectious phosphocalcic and cystine.
Conclusions: Urinary pH is a recognized factor in the scientific-urological community for the study, monitoring, treatment and prevention of lithiasic patients. Urinary pH measurement is a very useful tool, but test strips are not suitable for pH measurement and medical decision making. Currently, several studies have evaluated a new device to achieve the measurement of urinary pH effectively and easily by the patient, keeping urinary pH innon-lithogenic ranges with the association of medical and non-medical treatments, and good acceptability from the patients.
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Rev Esc Enferm USP
September 2025
Universidade de São Paulo, Escola de Enfermagem, São Paulo, SP, Brazil.
Objective: To identify pregnant women with urinary tract infections who are being monitored at a primary health care unit and their knowledge about antibiotics, as well as facilitating and challenging factors perceived by nurses that influence care, with a focus on antimicrobial resistance.
Method: Exploratory, descriptive study with a quantitative approach, involving pregnant women with urinary tract infections undergoing antibiotic treatment at a municipal health unit in São Paulo and nurses working at the same location. Data were obtained from computerized systems, medical records, and interviews, and were synthesized and analyzed using Microsoft Excel and Stata software.
Med Sci Sports Exerc
September 2025
Research Institute of Sport and Exercise Sciences (RISES), Liverpool John Moores University, Byrom Street, Liverpool, UNITED KINGDOM.
Background: Cannabidiol (CBD), a non-intoxicating phytocannabinoid, is used by athletes to enhance recovery and manage other conditions (e.g., poor sleep, anxiety).
View Article and Find Full Text PDFPLoS One
September 2025
Department of Nephrology, Chungnam National University, Daejeon, Republic of Korea.
Diabetic kidney disease (DKD) involves oxidative stress-driven damage to glomeruli (Gloms) and proximal convoluted tubules (PCT). NAD(P)H: quinone oxidoreductase 1 (NQO1) regulates redox balance, but its compartment-specific role remains unclear. Streptozotocin (STZ)-induced hyperglycemia increased albuminuria and foot process effacement, with NQO1 KO (NKO) mice exhibiting greater podocyte injury than WT, indicating exacerbated glomerular damage.
View Article and Find Full Text PDFIntroduction: The residual risk of chronic kidney disease (CKD) progression remains high in clinical trials of kidney protective drugs in patients with diabetic kidney disease (DKD).
Methods: In a prospective study, we assessed whether 16 plasma and 10 urine cytokine levels can inform the residual risk of CKD progression in 93 incident patients with DKD treated by Nephrology according to clinical guidelines.
Results: Plasma and urine levels of 12 plasma and 7 urinary cytokines differed between patients with DKD and from healthy controls.
J Urol
September 2025
Department of Urology, University of Michigan, Ann Arbor, Michigan.
Purpose: We assessed the effects of vaginal lasers for treating stress urinary incontinence (SUI) in women.
Materials And Methods: This systematic review and meta-analysis included randomized trials of women with SUI and assessed therapy with vaginal laser vs sham, control, or topical treatments.
Results: Nine studies of 689 women with SUI were included.