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Article Abstract
Galectin () is a member of a family of β-galactoside-binding lectin. The members of this family play important roles in the recognition of carbohydrate ligands and in various other biological processes. In this study, we identified the gene encoding in () and analyzed its expression in various tissues after pathogen challenge. Alignment analysis revealed that the two galactose-binding lectin domains of the deduced protein were highly conserved among all the teleosts. Phylogenetic analysis revealed that is most closely related to the gene of gilthead sea bream. was ubiquitously expressed in all tissues analyzed but was predominantly expressed in the spleen, head kidney, and intestine. After challenges with major microbial pathogens (, , or red sea bream iridovirus) of red sea bream, mRNA expression was significantly regulated in most immune-related tissues. These results suggested that not only plays an important role in the immune system of red sea bream but is also a possible inflammatory marker for pathogenic diseases.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827478 | PMC |
| http://dx.doi.org/10.3390/ani11010139 | DOI Listing |
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