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To evaluate the usefulness of the DSM-5 maladaptive personality domains in explaining the similarities and differences among four disorders included in the obsessive-compulsive spectrum, 428 Italian community-dwelling women (mean age = 31.96 years, SD = 12.30 years) were administered the Obsessive-Compulsive Spectrum Disorder Scales and the Personality Inventory for DSM-5-Short Form as part of an ongoing online survey on women's health. Multiple Indicators Multiple Causes (MIMIC) confirmatory bifactor analysis results showed that the OCSD general factor (i.e., obsessive-compulsive spectrum factor) was positively associated with Negative Affectivity, whereas Body Dysmorphic Disorder (BDD), Hoarding Disorder (HD), and Skin-Picking Disorder (SPD) specific factors showed significant and substantial differential relationships with dysfunctional personality domains. Specifically, BDD was positively associated with Negative Affectivity, Detachment and Psychoticism domains; HD was associated with high Negative Affectivity and Psychoticism; and SPD was associated with Detachment. © 2020 John Wiley & Sons, Ltd.
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http://dx.doi.org/10.1002/pmh.1502 | DOI Listing |
PLOS Ment Health
April 2025
Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, North Carolina, United States of America.
Large numbers of adults with mental disorders in the United States are incarcerated or otherwise involved with the criminal legal system. Evidence is lacking on prevalence of specific psychiatric diagnoses in this population. This article presents results from the Mental and Substance Use Disorders Prevalence Study (MDPS), a national epidemiological survey that assessed lifetime prevalence of schizophrenia-spectrum disorder, and past-year prevalence of bipolar 1, obsessive-compulsive, major depressive, generalized anxiety, and post-traumatic stress disorders using the Structured Clinical Interview for DSM-5 (SCID 5).
View Article and Find Full Text PDFNervenarzt
September 2025
Klinik für Psychiatrie, Psychotherapie und Psychosomatik des Kindes- und Jugendalters, Universitätsklinikum Freiburg, Medizinische Fakultät, Albert-Ludwigs-Universität Freiburg, Freiburg, Deutschland.
In the ICD-10 the developmental disorders are categorized under three different chapters: F7 for mental retardation, F8 for developmental disorders and F9 for disorders with onset in childhood and adolescence. In ICD-11 neurodevelopmental disorders represent the first new main classification group. The disorders grouped in these categories are all characterized by essentially genetically related atypical patterns of perception, emotional processing, cognition (general and social), language and motor skills.
View Article and Find Full Text PDFMol Psychiatry
August 2025
Kids Neuroscience Centre, The Children's Hospital at Westmead, Faculty of Medicine and Health, University of Sydney, Sydney, NSW, Australia.
Paediatric Acute-Onset Neuropsychiatric Syndrome (PANS) is characterised by abrupt onset obsessive compulsive disorder and regression in neurodevelopmental skills, triggered by infection or stress. Whether PANS is a distinct entity or part of a neurodevelopmental spectrum is uncertain, and its pathophysiology remains unclear. We show that children with PANS (n = 32) and other non-PANS (n = 68) neurodevelopmental disorders (total n = 100) have higher reported early childhood infections and a loss of previously acquired developmental skills compared to neurotypical controls (n = 58).
View Article and Find Full Text PDFInt J Mol Sci
August 2025
Department of Allergy, Immunology, Rheumatology, Division of Pediatrics, Stanford University School of Medicine, Palo Alto, CA 94305, USA.
Among the shared pathogenetic mechanisms leading to neurodevelopmental disorders (NDDs), a dysregulated inflammatory response has been described as a convergent pathway in NDDs. This scoping review was registered in the OSF database. It was conducted in accordance with the PRISMA Extension for Scoping Reviews, utilizing a comprehensive literature search of major academic databases, including PubMed and Web of Science.
View Article and Find Full Text PDFJ Med Biogr
August 2025
Obsessive, Compulsive, and Anxiety Spectrum Research Program, Institute of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Jeffry Hyman (1951-2001), an introvert boy from Queens, New York City, grew up to become one of the most iconic figures in New York's punk rock scene in the mid-1970s: Joey Ramone. In this study, we explored how Joey and his family coped with his health issues and peculiar behaviors, which were eventually identified as symptoms of obsessive-compulsive disorder (OCD). A narrative review of biographical sources was conducted to explore and infer the impact of Joey's OCD on his close relationships.
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