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Background: We sought to ascertain the short- and long-term results of total pericardiectomy for chronic constrictive pericarditis using a modified left anterolateral thoracotomy without cardiopulmonary bypass on postoperative low cardiac output, normalization of intracardiac pressures, survival, and reoperations.
Methods: Between January 2005 and December 2019 a series of 127 consecutive patients (91 male patients) between ages 4 and 72 years (median, 25 years; interquartile range, 18-38) underwent radical total pericardiectomy using a modified left anterolateral thoracotomy without cardiopulmonary bypass.
Results: Operative and late mortalities were 3.1% and 1.6%, respectively. Thirty-one patients (24.4%) had postoperative low cardiac output, and none required reoperations. At a median follow-up of 99 months (interquartile range, 56-141) the actuarial survival was 97.6% ± 0.01% months (95% confidence interval, 92.8-99.2). At their last follow-up 113 (93.4%) and 8 (6.6%) survivors were in New York Heart Association class I and II, respectively.
Conclusions: Total pericardiectomy is associated with lower perioperative and late mortality and decreased low cardiac output syndrome and confers significant long-term advantage of superior hemodynamics.
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http://dx.doi.org/10.1016/j.athoracsur.2020.10.045 | DOI Listing |
JACC Case Rep
June 2025
Center for Diagnosis and Treatment of Pericardial Diseases, Section of Cardiovascular Imaging, Robert and Suzanne Tomsich Department of Cardiovascular Medicine, Sydell and Arnold Miller Family Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA. Electronic address: kleina@
Background: Radiation-induced cardiovascular disease, a complication of mediastinal radiation, often results in valvular and pericardial disease. Management is challenging, especially in high-risk patients.
Case Summary: A 59-year-old man with a history of total body radiation presented with fatigue and dyspnea.
Ann Thorac Surg
September 2025
Division of Cardiac Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts. Electronic address:
Background: Postoperative atrial fibrillation (POAF) is the most common complication after cardiac surgery, occurring in 30%-50% of patients. Although previous studies have suggested a protective benefit from pericardiotomy and prophylactic amiodarone, these practices have not been widely adopted. The Pericardiotomy and Amiodarone for Prophylaxis against Postoperative Atrial Fibrillation (PAPPA) trial was designed to compare the incidence of POAF in cardiac surgery patients who receive a systematic pharmacosurgical prevention strategy vs standard of care.
View Article and Find Full Text PDFIndian Heart J
June 2025
Department of Cardiology, The Third People(')s Hospital of Chengdu, The Affiliated Hospital of Southwest Jiaotong University, Chengdu, China. Electronic address:
Objective: Low cardiac output syndrome (LCOS) is the leading cause of death after cardiac surgery. Studies have shown that 24% of postoperative mortality in patients undergoing pericardiectomy is attributed to LCOS. It is necessary to explore the risk factors of LCOS after pericardiectomy in patients with tuberculous constrictive pericarditis (CP).
View Article and Find Full Text PDFInterdiscip Cardiovasc Thorac Surg
May 2025
Department of Cardiac Surgery, University Heart Center Bonn, Bonn, Germany.
Objectives: Re-thoracotomy due to pericardial effusion is a frequent complication after aortic surgery, leading to prolonged intensive care unit (ICU) and hospital stays and adverse outcomes. This study aims to evaluate the frequency of re-thoracotomy and postoperative atrial fibrillation in patients undergoing ascending aorta replacement with or without posterior left pericardiotomy.
Methods: We retrospectively analysed clinical data from patients who underwent elective ascending aorta replacement with or without aortic root between January 2014 and June 2024.
Trials
April 2025
Department of Cardiothoracic Surgery, Guangxi Academy of Medical Sciences, The People's Hospital of Guangxi Zhuang Autonomous Region, 6 Taoyuan Road, Nanning, Guangxi, 530021, China.
Constrictive pericarditis is a result of chronic inflammation characterized by thickening and calcification of pericardial fibers, impaired diastolic filling, reduced cardiac output, and ultimately heart failure. The main objective of this multicenter trial is to evaluate whether conventional extracorporeal circulation pericardial resection has a better prognosis than pericardial resection without extracorporeal circulation. This study is a multicenter, randomized controlled, evaluator blinded, parallel group study with an advantageous framework.
View Article and Find Full Text PDF