Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.17843/rpmesp.2020.373.5753 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Evaluating the ergonomic aspects of laparoscopic energy devices: combination of a survey and a kinesiologic experiment.
Surg Endosc
September 2025
Department of Surgery and Cancer Research Institute, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
Introduction: This study aimed to evaluate surgeons' ergonomic satisfaction when using laparoscopic energy devices and to investigate how prolonged use affects muscle fatigue and surgical performance.
Methods: A two-part study, including a survey and a kinesiologic experiment, was conducted to compare 4 laparoscopic energy devices (D1-D4). Thirty surgeons completed a structured survey assessing ergonomic factors such as device weight, grip strength, handle design, comfort, and trigger location.
Artificial Intelligence in allergy and immunology: recent developments, implementation challenges, and the road towards clinical impact.
J Allergy Clin Immunol
September 2025
University of Groningen, University Medical Center Groningen, Beatrix Children's Hospital, Department of Pediatric Pulmonology and Pediatric Allergology, Groningen, the Netherlands; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC)
Artificial intelligence (AI) is increasingly recognized for its capacity to transform medicine. While publications applying AI in allergy and immunology have increased, clinical implementation substantially lags behind other specialties. By mid-2024, over 1,000 FDA-approved AI-enabled medical devices existed, but none specifically addressed allergy and immunology.
View Article and Find Full Text PDFEstablishing clinically relevant dissolution specifications for prodrug bioequivalence risk assessment: Integration of a dissolution/permeation system with physiologically based biopharmaceutics modeling in abiraterone acetate.
Eur J Pharm Biopharm
September 2025
Center of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing 210009, China. Electronic address:
Prodrugs with enzymatic activation requirements, such as the weakly basic biopharmaceutical classification system (BCS) class IV compound abiraterone acetate (ABA), face considerable bioequivalence (BE) risks owing to their pH-dependent solubility, food effects, and variable intestinal hydrolysis. This study established clinically relevant dissolution specifications for ABA using biorelevant dissolution and physiologically based biopharmaceutics modelling (PBBM). Two dissolution methods, two-stage (gastrointestinal transfer simulation) and single-phase (biorelevant media), were evaluated under fasted and fed conditions.
View Article and Find Full Text PDFGrowth deficits and craniofacial dynamics in preschool children with microcephaly: A comprehensive study.
Early Hum Dev
September 2025
Child Growth & Anthropology Unit, Department of Pediatrics, Postgraduate Institute of Medical Education & Research (PGIMER), Chandigarh, India. Electronic address:
Objectives: This study aimed to examine physical and craniofacial growth patterns in preschool-aged children with microcephaly and evaluate their potential clinical significance.
Methods: A total of 130 children (76 boys, 54 girls) aged 1-5 years with microcephaly (head circumference <-3 standard deviations) were enrolled in this prospective study at a tertiary care hospital, with 130 age- and sex-matched healthy controls. Nine craniofacial dimensions (head circumference, head length, head width, physiognomic facial length, morphological facial length, minimum frontal diameter, bizygomatic diameter, bigonial diameter, and total jaw height) were measured every six months using standardized techniques and instruments.