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http://dx.doi.org/10.1111/add.15347 | DOI Listing |
JACC Case Rep
September 2025
Department of Cardiovascular Surgery, Nagoya Heart Center, Nagoya, Japan.
Background: Capecitabine, an oral prodrug of 5-fluorouracil, is widely used for gastrointestinal malignancies. While its coronary toxicity is well documented, large-vessel complications such as aortic dissection are rarely reported.
Case Summary: We present a 65-year-old man with colorectal cancer who developed Stanford type A aortic dissection 3 days after initiating adjuvant capecitabine therapy.
J Thorac Oncol
August 2025
Department of Radiation Medicine, Markey Cancer Center, University of Kentucky, Lexington, Kentucky.
Introduction: Cigarette smoking negatively affects lung cancer prognosis. Incorporating smoking history into stage-stratified survival analyses may improve prognostication.
Methods: Using the International Association for the Study of Lung Cancer ninth edition NSCLC database, we evaluated the association between smoking status at diagnosis and overall survival (OS) using Kaplan-Meier plots and multivariate Cox proportional hazard regression models adjusted for age, region, sex, histologic type, performance status, and TNM stage.
Int J Vitam Nutr Res
July 2025
Institute of Cardiovascular Disease, China Three Gorges University, 443005 Yichang, Hubei, China.
Background: The effects of dietary niacin on the risk of cardiovascular disease (CVD) and mortality in patients with chronic kidney disease (CKD) remain unclear.
Methods: CKD patients with estimated glomerular filtration rates (eGFRs) 20-59 mL/min/1.73 m or urinary albumin/creatinine ratio ≥30 mg/g were identified in the National Health and Nutrition Examination Survey (NHANES) data from 2003 to 2018.
HIV AIDS (Auckl)
September 2025
Department of Respiratory Medicine, Beijing Ditan Hospital, Capital Medical University, Beijing, People's Republic of China.
Introduction: The advent of highly active antiretroviral therapy (HAART) has changed infection by human immunodeficiency virus (HIV) from an acute disease to a manageable chronic condition; however, pulmonary complications continue to affect patient quality of life. The goal of this research was to examine the link between CD4+ levels, viral load, and respiratory function in patients infected with HIV.
Methods: Patients were grouped as HIV-infected and non-infected (1:2 ratio).
J Surg Case Rep
September 2025
Department of Plastic Surgery and Hand Surgery, HOCH, Kantonsspital St Gallen, Rorschacherstrasse 95, 9007 St Gallen, Switzerland.
Vascularized reconstruction of bone defects in the foot after osteomyelitis is a complex procedure that requires an orthoplastic collaboration. This case demonstrates the successful use of a free osteocutaneous fibula flap with a perforator-based skin island to reconstruct the medial midfoot following a late-onset infection after fusion for osteonecrosis. A 63-year-old woman presented after osteonecrosis and failed surgeries, including talonavicular and naviculocuneiform arthrodesis complicated by infection.
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