Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Dicarbonyls are reactive precursors of advanced glycation endproducts. They are formed endogenously and during food processing. Currently, a comprehensive database on dicarbonyls in foods that covers the entire range of food groups is lacking, limiting knowledge about the amount of dicarbonyls that is ingested via food. The aim of this study was to analyze the dicarbonyls methylglyoxal (MGO), glyoxal (GO), and 3-deoxyglucosone (3-DG) in commonly-consumed products in a Western diet. We validated a UHPLC-MS/MS method to quantify MGO, GO, and 3-DG. We present a dietary dicarbonyl database of 223 foods and drinks. Total dicarbonyl concentrations were highest in dried fruit, Dutch spiced cake, and candy bars (>400 mg/kg). Total dicarbonyl concentrations were lowest in tea, dairy, light soft drinks, and rice (<10 mg/kg). The presented database of MGO, GO, and 3-DG opens the possibility to accurately estimate dietary exposure to these dicarbonyls, and explore their physiological impact on human health.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.foodchem.2020.128063 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Genetically modeled GLP1R and GIPR agonism reduce binge drinking and alcohol-associated phenotypes: a multi-ancestry drug-target Mendelian randomization study.
Mol Psychiatry
September 2025
Section on Clinical Genomics and Experimental Therapeutics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
Pharmacological modulation of glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) through dual GIP/GLP-1 receptor agonists, commonly used for diabetes and obesity, shows promise in reducing alcohol consumption. We applied drug-target Mendelian randomization (MR) using genetic variation at these loci to assess their long-term effects on problematic alcohol use (PAU), binge drinking, alcohol misuse classifications, liver health, and other substance use behaviors. Genetic proxies for lowered BMI, modeling the appetite-suppressing and weight-reducing effects of variants in both the GIPR and GLP1R loci ("GIPR/GLP1R"), were linked with reduced binge drinking in the primary (β = -0.
View Article and Find Full Text PDFPerchlorates as emerging contaminants: Sources, hazards, detection and remediation-An overview.
Chemosphere
September 2025
Department of Physical Chemistry and Technology of Polymers, Silesian University of Technology, 9 Strzody Street, 44-100 Gliwice, Poland. Electronic address:
Perchlorate contamination is a recent and significant issue in the context of environmental pollution. Perchlorates are mainly used as ingredients in solid propellants and pyrotechnic compositions. Perchlorate contamination of drinking water and food has recently become a human health concern, as studies have shown that they can interfere with the normal uptake of iodine by the thyroid gland, leading to a reduction in its production of triiodothyronine (T3) and thyroxine (T4) in vertebrates.
View Article and Find Full Text PDFIndividual and contextual characteristics associated with concurrent risk factors among adolescents: a multilevel cross-sectional study based on the 2019 Brazilian National Health Survey.
Epidemiol Serv Saude
September 2025
Universidade Federal do Piauí, Picos, PI, Brazil.
Objective: To assess the simultaneity of risk behaviors for chronic non-communicable diseases and their association with individual and contextual characteristics in Brazilian adolescents.
Methods: Cross-sectional study using data from the 2019 Brazilian National Health Survey. The simultaneity of factors of the consumption of ultra-processed foods, level of physical activity, smoking and alcohol use was analyzed, according to individual and contextual characteristics, estimating the odds ratios (OR) and respective 95% confidence intervals (95%CI) for fixed effects and variance and 95%CI for random effects, through multilevel polytomous logistic regression.
Wood vinegar as a natural alternative to antibiotics: Effects on cecal microbiota, antioxidant status, and nutrient digestibility in broiler chickens.
Vet World
July 2025
Department of Animal Science, Faculty of Agriculture, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia.
Background And Aim: Antibiotic resistance has spurred interest in alternative feed additives for poultry. Wood vinegar (WV), a by-product of plant pyrolysis, contains bioactive compounds with antioxidant and antimicrobial properties. This study aimed to evaluate the effects of WV supplementation through drinking water on the cecal microbial population, volatile fatty acid (VFA) concentrations, antioxidant enzyme activity, and apparent ileal nutrient digestibility in broiler chickens.
View Article and Find Full Text PDFAssociated factors for exertional heat exhaustion-related symptoms among amateur golfers in Japan: A retrospective case-control study.
Temperature (Austin)
June 2025
Kanto Golf Association, Chuo-ku, Tokyo, Japan.
The associated factors for exertional heat stroke among amateur golfers remain poorly understood. We conducted a case-control study to examine exertional heat exhaustion (EHE) - related symptoms among amateur golfers in Japan using a self-administered questionnaire. Retrospective case-control study design.
View Article and Find Full Text PDF