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The purpose of the current study was to evaluate the physicochemical properties, digestive stability, storage stability, and intestinal absorption of formulated natural vitamins (FNV) by mixing fat-soluble vitamins extracted from agricultural products with their synthetic vitamin (SYNV) counterparts using a 6 to 4 ratio (w:w, dry weight). The FNV A, D, E, and K were evenly dispersed without crystal growth in the dispersion specifications for the functional tablet foods. The FNV A, D, E, and K had 89, 73, 65, and 36% of the digestive recovery, respectively, which was comparable to that of the SYNV. FNV D, E, and K were retained over 77%, but rapidly decreased to 15% after 6 months during accelerated storage at 25 30 and 35℃. The comparable radical scavenging capacity was found between the FNV and the SYNV. Results from the current study suggest that fat-soluble vitamins extracted from agricultural products could be reasonable complementary use for natural vitamin supplements.
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http://dx.doi.org/10.1002/fsn3.1804 | DOI Listing |
Front Reprod Health
August 2025
Department of Medical Laboratory Science, Afe Babalola University, Ado-Ekiti, Nigeria.
Background: Vitamin D, sometimes referred to as the "sunshine vitamin", is well-known for its role in maintaining bone health processes that are highly dependent on calcium regulation. However, there is an emerging wealth of evidence that this fat-soluble vitamin has an important role in male sexual health regarding erectile function, production of testosterone, and overall fertility. Due to the increased vitamin D deficiency rates in most populations, the implications of its deficiency on male sexual functions have gained great interest.
View Article and Find Full Text PDFClin Nutr
August 2025
Department of Nephrology, Naval Medical Center of the People's Liberation Amy (PLA), Naval Medical University, Shanghai, China. Electronic address:
Background: Micronutrient deficiencies are common in patients undergoing maintenance hemodialysis (MHD), potentially contributing to adverse clinical outcomes. Hemodiafiltration with endogenous reinfusion (HFR) integrates convection, diffusion, and adsorption, potentially preserving essential nutrients better than traditional online hemodiafiltration (HDF). This study aimed to compare the acute effects of HFR and HDF on serum micronutrient concentrations in MHD patients.
View Article and Find Full Text PDFClin J Am Soc Nephrol
September 2025
Department of Precision Medicine, NYU Langone Health, New York, NY.
Background: Children with chronic kidney disease (CKD) experience poor growth and development via multiple mechanisms. We aimed to describe deficiencies in dietary micronutrient intake and associate dietary micronutrient intake with metabolic pathways.
Methods: The Chronic Kidney Disease in Children cohort study enrolled participants six months to 16 years with CKD stage 2-4 across North America.
World J Methodol
December 2025
Department of Pharmacy, Campbell University College of Pharmacy & Health Sciences, Buies Creek, NC 27506, United States.
Micronutrients are fundamental to support and maintain normal physiological function. Deficiencies of these nutrients are a growing public health concern with potentially devastating consequences. An adequate diet of whole foods is the primary source of micronutrients; supplementation is sometimes necessary.
View Article and Find Full Text PDFBMC Nutr
September 2025
Department of Biomedical and Clinical Sciences, University of Milano, Milano, 20157, Italy.
Background: Up to now, scientific literature has not reported studies evaluating the efficacy of polyglucosamine L112 on body weight, insulin resistance, and cholesterol levels in patients with metabolic syndrome, despite its known antioxidant properties and potential to reduce these parameters, making it a promising candidate for treating metabolic syndrome.
Objective: The aim of this study was to examine the activity of L112 in a subgroup of cases suffering from metabolic syndrome (MS).
Methods: A subgroup of 26 subjects (8 males and 18 females; age 55 ± 11.