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Although much is known about cardiovascular patients' medication adherence, the extent to which clinicians perceive non-adherence as a barrier in clinical practice is little explored. Objective To evaluate knowledge and awareness about potential barriers to medication adherence, and to evaluate strategies used in clinical practice by Portuguese clinicians on how to foster medication adherence of patients undergoing secondary cardiovascular prevention. Setting Nominal Group Technique (NGT) at the University of Lisbon; online survey addressed to physicians working in primary and secondary care in Portugal. Method A narrative literature review was conducted in Pubmed to identify studies describing interventions targeted at physicians to manage medication adherence. The NGT included 12 allied healthcare professionals with recognized expertise in medication adherence and was organised in four phases, resulting in survey development. The survey was used in a cross-sectional national study where clinicians reported their knowledge and perceptions about patients' medication adherence and their daily practice. Main outcome measures Knowledge and awareness about barriers to medication adherence; and practice patterns. Results A total of 296 papers were identified, 26 of which were included. Four main topics were selected to be used in the NGT: adherence determinants, detecting non-adherence, fostering adherence, and educating physicians. NGT resulted in a survey, reaching 451 physicians, mostly practicing in primary care. Most had specific education on medication adherence and considered patient interviews and prescription records the most useful assessment methods. Nonetheless, many recognised often using clinical judgement to evaluate adherence in practice. Barriers to medication adherence were perceived to occur often during implementation. Most perceived reasons for uncontrolled hypertension were non-adherence to lifestyle recommendations and to medication. Less than half the physicians asked their patients if medication was taken. More useful enabling strategies included reducing daily doses, reviewing therapeutic options and motivational interventions. Conclusions Clinicians seem well informed about the importance of medication adherence and aware of problems encountered in practice. Limited time during medical appointment may be a barrier for better patient support.
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http://dx.doi.org/10.1007/s11096-020-01174-2 | DOI Listing |
Eur J Clin Pharmacol
September 2025
Department of Clinical Pharmacy and Pharmacology, University of Groningen, and University Medical Center Groningen, Groningen, The Netherlands.
Purpose: Non-adherence to inhaled medication poses a significant clinical and economic burden on patients with respiratory diseases. This narrative review provides an overview of key aspects of hair analysis, in general and specific for inhaled medications, and explores the potential of hair analysis as a novel tool to monitor adherence to inhaled medications.
Methods: PubMed searches were conducted to explore four aspects: (1) mechanisms of (inhaled) drug's systemic absorption and deposition in hair; (2) quantification of drugs in hair; (3) factors impacting (inhaled) drug hair concentrations; and (4) clinical studies assessing inhaled medication adherence through hair analysis.
J Korean Med Sci
September 2025
Department of Neurology, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea.
Background: Readily available treatments for Alzheimer's disease and related dementia (ADRD) include acetylcholinesterase inhibitors and N-methyl-D-aspartate receptor antagonists. Non-adherence and early discontinuation of anti-dementia medications are prevalent issues. We aimed to investigate factors associated with suboptimal usage of anti-dementia medications in ADRD.
View Article and Find Full Text PDFCureus
August 2025
Community Medicine Management, Shimane University, Izumo, JPN.
This systematic review synthesized findings from 17 studies conducted between 2000 and 2024, focusing on the definitions, interventions, and outcomes associated with community nursing. The studies originated from diverse countries, including Singapore, Australia, Italy, Portugal, and the United States, and employed various designs such as quasi-experimental trials, pre-post evaluations, and descriptive studies. Sample sizes ranged from 23 to over 1,600 participants, with most targeting older adults or individuals with chronic conditions.
View Article and Find Full Text PDFS Afr Fam Pract (2004)
August 2025
Department of Family Medicine, Faculty of Health Sciences, University of Limpopo, Mankweng.
Background: Non-adherence to treatment remains a major contributing factor to uncontrolled hypertension and its complications. In South Africa, an estimated 50% of adults are living with hypertension and between 41.9% and 45.
View Article and Find Full Text PDFJ Med Syst
September 2025
Department of Nursing, ESEP - Porto Higher School of Nursing, Rua Dr. António Bernardino de Almeida, nº 830, Porto, 4200-072, Portugal.
To address the challenges of self-care in oncology, gamification emerges as an innovative strategy to enhance health literacy and self-care among individuals with oncological disease. This study aims to explore and map how gamification can promote health literacy for self-care of oncological diseases. A scoping review was conducted following the Joanna Briggs Institute guidelines and the PRISMA-ScR Checklist developed for scoping reviews.
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