Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
COVID-19 is a complex and heterogeneous disease. The pathogenesis and the complications of the disease are not fully elucidated, and increasing evidence shows that SARS-CoV-2 causes a systemic inflammatory disease rather than a pulmonary disease. The management of hospitalized patients in COVID-19 dedicated units is advisable for segregation purpose as well as for infection control. In this article we present the standard operating procedures of our COVID-19 high dependency unit of the Policlinico Hospital, in Milan. Our high dependency unit is based on a multidisciplinary approach. We think that the multidisciplinary involvement of several figures can better identify treatable traits of COVID-19 disease, early identify patients who can quickly deteriorate, particularly patients with multiple comorbidities, and better manage complications related to off-label treatments. Although no generalizable to other hospitals and different healthcare settings, we think that our experience and our point of view can be helpful for countries and hospitals that are now starting to face the COVID-19 outbreak.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545383 | PMC |
| http://dx.doi.org/10.1186/s12931-020-01516-8 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Health Inequity in People with Cystic Fibrosis: Can We Close the Gap?
Ann Am Thorac Soc
September 2025
Hadassah Medical Center, Pediatric Pulmonology Unit and Cystic Fibrosis Center, Jerusalem, Jerusalem, Israel.
Background Although advances in care have improved cystic fibrosis (CF) outcomes in higher-income countries (HICs), the situation remains alarming in lower-income countries (LICs). Methods People with CF (pwCF) enrolled in the European Cystic Fibrosis Society Patient Registry (ECFSPR) and carrying at least one F508del variant allele were evaluated in 2017 and in 2022 for predicted percent forced expiratory volume (ppFEV1), underweight status, and chronic Pseudomonas aeruginosa (Pa) infection, according to the gross national income (GNI) per capita divided into three terciles (low-income countries, LICs; middle-income countries, MICs; and high-income countries, HICs). Survival was evaluated in the periods 2013-2017 and 2018-2022.
View Article and Find Full Text PDFEffect of Samarium Doping on the Energy Storage Properties of Bismuth Sodium Titanate-Based Lead-Free Ceramics.
ACS Appl Mater Interfaces
September 2025
School of Engineering and Materials Science, Queen Mary University of London, Mile End Road, London E1 4NS, U.K.
Lead-free electroceramics have attracted significant research interest as alternatives to lead-containing systems due to concerns related to lead's toxicity to human health and the environment. Solid solutions based on bismuth sodium titanate (BNT) and barium titanate (BT), particularly those with compositions near the morphotropic phase boundary (MPB), such as 0.94 BiNaTiO-0.
View Article and Find Full Text PDFOrganocatalytic Halogenation of Indazoles and Pyrazoles with -Halosuccinimides Enhanced by Gallocyanine as Halogen-Transfer Agent.
J Org Chem
September 2025
Department of Chemistry and Biochemistry, The University of Tulsa, 800 S. Tucker Dr., Tulsa, Oklahoma 74104, United States.
A screening of organic dyes has led to the discovery of gallocyanine as an organocatalyst for the halogenation of a variety of functionalized pyrazoles, indazoles, and aromatics. This work provides an example of a mild organocatalyst that does not require light, oxidizing agents, transition-metal activation, or high temperatures. Thirty-nine halogenated pyrazoles and indazoles, including pharmaceuticals such as celecoxib, deracoxib, and antipyrine, have been isolated in good to excellent yields using -halosuccinimides as the stoichiometric halogen source with gallocyanine as the catalyst.
View Article and Find Full Text PDFTRANSLATION, CULTURAL ADAPTATION, AND SEMANTIC VALIDATION OF THE PEDIATRIC NEUROGENIC BOWEL DYSFUNCTION SCORE (NDBS) INTO BRAZILIAN PORTUGUESE AND A PILOT STUDY.
Arq Gastroenterol
September 2025
Escola Superior de Ciências da Saúde, Fundação de Ensino e Pesquisa em Ciências da Saúde, Brasília, DF, Brasil.
Objectives: This study aimed to translate the Neurogenic Bowel Dysfunction Score into Brazilian Portuguese, adapting it culturally and validating it semantically.
Methods: The process followed international guidelines for translation, back-translation, cultural adaptation, and semantic validation, involving a committee of specialists and a pre-test with 10 Brazilian pediatric patients with neurogenic bowel dysfunction (mean age: 11 years). Participants were divided into two groups, depending on whether they used transanal irrigation for intestinal management.
Multistate Ferroelectricity Enabled by Electrically Controlled Phase Transition of Two-Dimensional Ices.
Phys Rev Lett
August 2025
Nanjing University of Aeronautics and Astronautics, State Key Laboratory of Mechanics and Control for Aerospace Structures and Key Laboratory for Intelligent Nano Materials and Devices of the Ministry of Education, Institute of Nano Science, Nanjing, 210016, China.
Multistate ferroelectric polarization holds promise for realizing high-density nonvolatile memory devices, but so far is restricted to a few traditional ferroelectrics. Here, we show that nanoconfined two-dimensional (2D) ferroelectric ice can achieve phase-dependent multistate polarization through extensive classical and ab initio molecular dynamics simulations. An in-plane electric field is found to induce the reversible transition between a low-polarization AA-stacked hexagonal ice phase and an unprecedented high-polarization AB-stacked ice phase, resulting in a four-state ferroelectric switching pathway.
View Article and Find Full Text PDF