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Keeping the human body in a thermal comfort state inside a room has become a challenge in recent years. While the most common strategy is to heat buildings, it requires a lot of energy. Reducing this energy consumption will have positive impacts, both economically and environmentally. We propose here to act directly on the personal thermal heating of the human body, by modulating the absorption and transmission properties of a synthetic polymer membrane in the mid-infrared (MIR). We show numerically that 5% SiO submicron particles inserted in polyethylene (PE) and nanoporous polyethylene (nanoPE) membranes increase the radiative heating of the membrane, reducing the required ambient temperature of a room by more than 1.1 °C. The proposed membrane can be flexible enough to be easily integrated into conventional textiles.
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http://dx.doi.org/10.3390/nano10101968 | DOI Listing |
J Environ Pathol Toxicol Oncol
January 2025
Pharmacology and Drug Discovery Research Laboratory, Division of Life Sciences; Institute of Advanced Study in Science and Technology (IASST), An Autonomous Institute under - Department of Science & Technology (Govt. of India).
Iron is an essential trace element for the human body, but having too much or too little of it can cause various biological issues. When ferrous ions react with hydrogen peroxide, they create highly reactive and soluble hydroxyl radicals that can damage cells through oxidation. This reaction, known as the Fenton reaction, can cause lipid peroxidation and ferroptosis.
View Article and Find Full Text PDFNeurology
October 2025
Alzheimer's Disease and Other Cognitive Disorders Unit, Department of Neurology, Hospital Clínic de Barcelona, Fundació Recerca Clínic Barcelona-IDIBAPS, Spain.
Background And Objectives: α-Synuclein seed amplification assays (αSAAs) can improve the diagnosis of synucleinopathies and detect α-synuclein (αSyn) copathology in vivo in clinical practice. We aimed to evaluate the diagnostic performance of αSAA for detecting αSyn in CSF for diagnosing dementia with Lewy bodies (DLB) in a clinical cohort of cognitively impaired individuals. We explored how the coexistence of Alzheimer disease (AD) and αSyn pathology influences biomarker levels and clinical profiles.
View Article and Find Full Text PDFJ Clin Oncol
September 2025
Carole Mercier, MD, and Charlotte Billiet, MD, PhD, Department of Radiation Oncology, Iridium Network, Wilrijk, Antwerp, Belgium, Integrated Personalised and Precision Oncology Network, University Antwerp, Antwerp, Belgium; Charlotte Billiet, MD, PhD, Department of Radiation Oncology, Iridium Networ
PLoS Negl Trop Dis
September 2025
Programa de Patologia Ambiental e Experimental, Universidade Paulista (UNIP), São Paulo, Brasil.
Microsporidia causes opportunistic infections in immunosuppressed individuals. Mammals shed these spores of fungi in feces, urine, or respiratory secretions, which could contaminate water and food, thereby reaching the human body and causing infection. The oral route is the most common route of infection, although experiments have demonstrated that intraperitoneal and intravenous routes may also spread infection.
View Article and Find Full Text PDFPLoS One
September 2025
Department of Hygiene, Kawasaki Medical School, Kurashiki, Japan.
T-cell therapies have proven to be a promising treatment option for cancer patients in recent years, especially in the case of chimeric antigen receptor (CAR)-T cell therapy. However, the therapy is associated with insufficient activation of T cells or poor persistence in the patient's body, which leads to incomplete elimination of cancer cells, recurrence, and genotoxicity. By extracting the splice element of PD-1 pre-mRNA using biology based on CRISPR/dCas13 in this study, our ultimate goal is to overcome the above-mentioned challenges in the future.
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