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Aims: To characterize psychologic functioning across five chronic overlapping pain conditions (COPCs)-temporomandibular disorders, fibromyalgia, low back pain, headache, and irritable bowel syndrome-and their overlaps.
Methods: Participants were 655 adults in the OPPERA study. Psychologic variables were standardized in separate logistic regression models to compare their relative strength of association with each COPC. Random forest regression was used to explore the association of all psychologic measures with COPCs simultaneously. Linear regression analyses examined whether the count of COPCs was associated with psychologic measures.
Results: In univariate and multivariable analyses, measures of somatic symptom burden showed the strongest associations with individual COPCs and with the number of COPCs. Additional psychologic variables that showed significant associations with individual COPCs and their overlap included negative mood, perceived stress, and pain catastrophizing.
Conclusion: These findings highlight the importance of psychologic functioning in the assessment and management of these overlapping pain conditions.
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http://dx.doi.org/10.11607/ofph.2584 | DOI Listing |
J Am Acad Orthop Surg Glob Res Rev
September 2025
From the American Hip Institute Research Foundation (Dr. Quesada-Jimenez, Dr. Kahana-Rojkind, and Dr. Domb), and the American Hip Institute, Chicago, IL (Dr. Domb).
Hip pain after a total hip arthroplasty is a prevalent condition. Once aseptic loosening and infection have been ruled out, the possible entities are vast. Accurate diagnosis in this patient population is challenging because they might present in different stages of their recovery process and the potential overlap of some conditions.
View Article and Find Full Text PDFInt J Gynaecol Obstet
September 2025
Department of Obstetrics and Gynecology, David Geffen School of Medicine at the University of California, Los Angeles, California, USA.
The goal was to develop a pragmatic classification system for conditions associated with chronic pelvic pain (CPP), aiming to enhance diagnosis, management, education, and research of CPP. An international, multidisciplinary panel participated in a modified RAND/UCLA Delphi consensus. This panel included healthcare professionals, medical society representatives, experts, individuals with lived experience of pain, advocacy groups, researchers, educators, and journal editors.
View Article and Find Full Text PDFZhonghua Bing Li Xue Za Zhi
September 2025
Department of Pathology, Clinical Oncology School of Fujian Medical University/Fujian Cancer Hospital, Fuzhou 350014, China.
To explore the clinical features, histopathological morphology, and differential diagnosis of lymphoepithelioma-like carcinoma with abnormal expression of follicular dendritic cell markers. From 2020 to 2021, 4 cases of lymphoepithelioma-like carcinoma with abnormal expression of follicular dendritic cell markers diagnosed in Fujian Cancer Hospital (2 cases) and the Second Affiliated Hospital of Fujian Medical University (2 cases) were collected. Different ancillary procedures such as HE, special stains, immunohistochemistry, and in situ hybridization techniques were used to assess the histopathological features and immunophenotypes.
View Article and Find Full Text PDFPLoS Negl Trop Dis
September 2025
División de Inmunología, Programa de Medicina, Facultad de Ciencias de la Salud, Universidad Surcolombiana, Neiva, Huila, Colombia.
Background: Dengue and chikungunya are arboviral diseases with overlapping clinical characteristics. Dengue virus (DENV) is endemic in Colombia, and in 2014/2015, the chikungunya virus (CHIKV) caused an epidemic that resulted in over 350,000 cases. Since then, both viruses have been actively co-circulating.
View Article and Find Full Text PDFFront Pain Res (Lausanne)
August 2025
University Otolaryngology, Providence, RI, United States.
Background: Rhinosinusitis (RS) is a leading reason for antibiotic prescriptions but treatment satisfaction is low. Misdiagnosis may contribute to poor outcomes, as migraine-often underrecognized-can mimic RS symptoms, with studies showing overlap between RS and migraine diagnoses. Our aims were to explore the demographics and clinical features of facial pain or pressure (FPP), its relationship with migraine and RS, and distinguish symptoms between these overlapping conditions.
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