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New HIV infections associated with injection drug use are of major concern in rural US communities. This study explores acceptability of, consent for, and uptake of free at-home HIV testing among people who use drugs (PWUD) in one of the nation's epicenters for drug-related harms and HIV vulnerability: Rural Central Appalachia. Eligible participants were 18-35 years old, lived in Appalachian Kentucky, and reported using opioids to get high in the previous 30 days. A majority reported being likely (63.6%, 96/151) to take a free at-home HIV tests and 66.9% (101/151) consented to receive one. Among those who were randomly selected to receive a Home Access HIV-1 test kit (n = 37), 37.8% mailed in blood spots and 21.6% called to receive results. This study provides evidence that PWUD may be willing to take an at-home test, but other barriers may inhibit actual completion.
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http://dx.doi.org/10.1007/s10461-020-03034-6 | DOI Listing |
PLoS One
August 2025
Division of Prevention Sciences, School of Medicine, University of California San Francisco, San Francisco, California, United States of America.
Unhealthy alcohol use is prevalent in sub-Saharan Africa and can worsen poverty, couple relationships, and HIV treatment outcomes. In response, we assessed participant experiences with Mlambe, a pilot study of an economic and relationship-strengthening intervention for couples living with unhealthy alcohol use and HIV. Exit interviews were conducted with a subset of 20 couples who participated in a pilot trial of Mlambe in Zomba, Malawi.
View Article and Find Full Text PDFLancet Prim Care
July 2025
Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.
Background: A previous trial showed that intermittent preventive treatment with dihydroartemisinin-piperaquine (IPTp-DP) was more effective than the current policy of single screening and treatment in preventing malaria during pregnancy in Papua, Indonesia. The STOPMiP-2 study evaluated the Ministry of Health pilot implementation of IPTp-DP through routine antenatal care in Papua.
Methods: A mixed-method evaluation was conducted in ten primary health-care facilities in the Mimika district in Papua, Indonesia from June 8, 2022, to Dec 27, 2023.
Int J STD AIDS
August 2025
Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
BackgroundRates of sexually transmitted and blood borne infections (STBBI) are rapidly increasing. Despite the high diagnostic accuracy of self-testing, no fully remote STBBI testing programs are available in Canada. We aimed to evaluate the feasibility and acceptability of a fully-remote, web-based, at-home STBBI testing (self-collection) program in Calgary, Canada.
View Article and Find Full Text PDFAIDS Behav
August 2025
Department of Medicine, Division of Infectious Diseases, Washington University School of Medicine, 4523 Clayton Avenue, 63110, Saint Louis, MO, USA.
This study investigated the impact of COVID-19-related disruptions to healthcare systems on engagement with HIV care among people enrolled in treatment at a university hospital's infectious disease (ID) clinic. Clinical outcome data from January 2019 to December 2020 were analyzed, and in-depth, semi-structured interviews were conducted from March 2021 to October 2021 with 20 participants enrolled in HIV care at the clinic. Informal interviews were conducted with seven people who work directly with clients at the ID clinic and similar settings to inform the refinement of the interview guide and support the triangulation of findings.
View Article and Find Full Text PDFJ Acquir Immune Defic Syndr
August 2025
Department of Medicine; University of California, San Francisco; 94143; USA.