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In 2016 we reported evidence for associative learning in plants (Gagliano et al., 2016). In view of the far-reaching implications of this finding we welcome the attempt made by Markel to replicate our study (Markel, 2020). However, as we discuss here, the protocol employed by Markel was unsuitable for testing for associative learning.
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http://dx.doi.org/10.7554/eLife.61141 | DOI Listing |
J Colloid Interface Sci
September 2025
School of Electronic Information & Artificial Intelligence, Shaanxi University of Science and Technology, Xi'an 710021, China.
The integration of information memory and computing enabled by nonvolatile memristive device has been widely acknowledged as a critical solution to circumvent the von Neumann architecture limitations. Herein, the Au/NiO/CaBiTiO/FTO (CBTi/NiO) heterojunction based memristor with varying film thicknesses are demonstrated on FTO/glass substrates, and the CBTi/NiO-4 sample shows the optimal memristor characteristics with 5 × 10 stable switching cycles and 10-s resistance state retention. The electrical conduction in the low-resistance state is dominated by Ohmic behavior, while the high-resistance state exhibited characteristics consistent with the space-charge-limited conduction (SCLC) model.
View Article and Find Full Text PDFFront Aging Neurosci
August 2025
Laboratory of Molecular Neurodegeneration, Graduate School of Biomedical Systems and Technologies, Institute of Biomedical Systems and Biotechnology, Peter the Great St. Petersburg Polytechnic University, Saint Petersburg, Russia.
Alzheimer's disease (AD) is a neurodegenerative disorder that leads to progressive cognitive decline and significant disruptions in hippocampal neural networks, critically impacting memory and learning. Understanding the neural mechanisms underlying these impairments is essential for developing effective therapies. The 5xFAD mouse model, known for progressive neurodegeneration and cognitive deficits, provides a valuable platform for investigating associative learning and memory impairments related to AD.
View Article and Find Full Text PDFProg Neuropsychopharmacol Biol Psychiatry
September 2025
Institut de Neurociències, Universitat Autònoma de Barcelona, Barcelona, Spain; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Madrid, Spain; Unitat de Neurociència Traslacional, Parc Taulí Hospital Universitari, Institut d'Investigació i Innovació Parc Taulí (I3PT), S
The appearance of long-lasting behavioral alterations is considered critical for the characterization of acute stressors as putative animal models of PTSD. However, the traumatic nature of the different stressors used is objectively difficult to demonstrate and literature is plagued by inconsistent results. In the present study we wanted to demonstrate the relevance of qualitative aspects of stressors not linked to their severity (as evaluated by classical biological markers) and how the use of different mouse or rat strains can contribute to the inconsistencies.
View Article and Find Full Text PDFMem Cognit
September 2025
Department of Psychology, University of Hildesheim, Universitätsplatz 1, 31141, Hildesheim, Germany.
Previous olfactory paired-associate (PA) studies showed that odors are less effective associative cues than other sensory modalities. It has been suggested that odor familiarity might improve memory stability, thereby facilitating PA memory performance. In the current study, we designed three experiments to investigate whether enhanced odor familiarity would also enhance the effectiveness of odors in a PA memory paradigm.
View Article and Find Full Text PDFbioRxiv
August 2025
Department of Biology, Brandeis University, Waltham, MA 02453, USA.
The ability to update the valence of sensory perception to influence behavior is crucial for survival. A common phenotype in autism spectrum disorders (ASDs) is defects in sensory processing, but whether these defects impair flexible sensory encoding is largely unexplored. In particular, how genetic risk factors such as deletion affect the adaptability of cortical taste processing and downstream behavior is unknown.
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