Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Objectives: Congenital cytomegalovirus (cCMV) infection can be easily prevented by hygienic measures. Up to date the majority of the studies in literature highlighted a reduction in cCMV antenatal counseling and its prevention. Our purpose was to evaluate obstetrics providers' knowledge about cCMV infection, management and the behavioral practices to avoid it.

Methods: This is a cross-sectional survey carried out in Umberto I Hospital, "Sapienza" University of Rome between November 2019 and January 2020. We recruited 148 specialists and residents in Obstetrics and Gynecology through online anonymous multiple-choice 13-questions, 10 min-survey comparing responses between the two groups.

Results: A total of 94.6% of all participants said they always prescribe cytomegalovirus (CMV) serum screening: 73.6% of them regularly counsel about preventive practices, with specialists recording higher percentages (85.4 vs. 65.1%, p<0.005). We identified a good knowledge about the diagnostic pathway, but only 58.1% of our population knows the correct time of late amniocentesis. 12.2% of providers do not consider magnetic resonance (MRI) as a complementary exam.

Conclusions: Prevention of maternal seroconversion is crucial: even if our data show an acceptable knowledge about antenatal counseling, we encourage clinicians to firmly inform and educate women about behavioral measures.

Download full-text PDF

Source
http://dx.doi.org/10.1515/jpm-2020-0224DOI Listing

Publication Analysis

Top Keywords

obstetrics providers'
8
providers' knowledge
8
preventive practices
8
congenital cytomegalovirus
8
ccmv infection
8
observational study
4
study assess
4
assess italian
4
italian obstetrics
4
knowledge preventive
4

Similar Publications

The global surge in the population of people 60 years and older, including that in China, challenges healthcare systems with rising age-related diseases. To address this demographic change, the Aging Biomarker Consortium (ABC) has launched the X-Age Project to develop a comprehensive aging evaluation system tailored to the Chinese population. Our goal is to identify robust biomarkers and construct composite aging clocks that capture biological age, defined as an individual's physiological and molecular state, across diverse Chinese cohorts.

View Article and Find Full Text PDF

RO8191, a new compound for initiating embryo implantation in mice.

Sci Rep

September 2025

Laboratory of Animal Morphology, Department of Animal Sciences, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya, 464-8601, Aichi, Japan.

During early pregnancy in mice, leukemia inhibitory factor (LIF) regulates embryo implantation by activating the JAK/STAT3 signaling pathway. The STAT3 pathway has been recognized to play a critical role in embryo implantation; however, it remains unclear whether STAT3 activation alone is sufficient to induce implantation. In this study, we investigated the effects of RO8191, a potential STAT3 activator, on embryo implantation through a series of studies with different mouse models.

View Article and Find Full Text PDF

The maternal microbiome during pregnancy and the peripartum period plays a critical role in maternal health outcomes and establishing the neonatal gut microbiome, with long-term implications for offspring health. However, a healthy microbiome during these key periods has not been definitively characterized. This longitudinal study examines maternal and neonatal microbiomes using 16S rRNA amplicon sequencing in a Japanese cohort throughout pregnancy and the postpartum period.

View Article and Find Full Text PDF

ObjectivePseudoexfoliation syndrome is a systemic disease of unknown etiology, seen in advanced ages, characterized by extracellular material accumulation in ocular tissues and visceral organs. Autophagy, which is a basic metabolic pathway, provides macromolecule recycling of the cell and maintains cell homeostasis by adapting to the cell's stress environment. The aim of this study was to examine the relationship between specific mechanisms of autophagy and pseudoexfoliation syndrome.

View Article and Find Full Text PDF

Integrated multi-omics analysis dissects di-isobutyl phthalate exposure-induced male fertility impairment.

Ecotoxicol Environ Saf

September 2025

Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Qilu Hospital of Shandong University, 107 Wenhua West Road, Jinan, Shandong 250012, China; Shandong Key Laboratory of Reproductive Health and Birth Defects Prevention and Control, China. Electronic address:

Di-isobutyl phthalate (DiBP), a member of the phthalate esters, is frequently used in manufacturing consumer and industrial products as plasticizer to improve durability and flexibility. Despite much research, little is known about the direct mechanisms by which DiBP harms the male reproductive system. In the present study, a male ICR mice model was developed to investigate the reproductive effect and mechanism of DiBP exposure, followed by transcriptomics, non-targeted metabolome, and 16S rDNA sequencing accordingly.

View Article and Find Full Text PDF