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We examined the characteristics, motivations, and harms associated with celebrating events at off-campus parties (OCPs), including a particularly harmful off-campus block party compared to on-campus parties (CPs). Survey with a representative sample of 491 students in Canada. Three focus groups with a total of 14 students who have attended the OCBP and one focus group with community members affected by the OCBP ( = 10). 14.3% of students attended OCPs. OCPs were significantly more likely to be associated with harms. Focus groups revealed that students attend the OCBP as it is cheaper to consume alcohol compared to CPs. Improved music was the most common solution to improve CP. Community members identified 16 potential solutions to mitigate the harms and prevent the OCBP. Reducing costs and improving the experience may increase likelihood of students attending CPs and minimize harms of OCPs.
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http://dx.doi.org/10.1080/07448481.2020.1784908 | DOI Listing |
Bioorg Chem
September 2025
Department of Medicinal Chemistry, Shandong Key Laboratory of Druggability Optimization and Evaluation for Lead Compounds, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, Shandong, PR China. Electronic address:
A series of novel 3,3-dimethyl-2,3,4,9-tetrahydro-1H-carbazole derivatives were rationally designed, synthesized and evaluated for their biological activity as AcrB inhibitors. The compounds were assessed for their antibiotic potentiating effects, followed by evaluation of Nile Red efflux inhibition, and off-target effects including activity on the outer and inner bacterial membranes. Ten compounds potentiated antibiotic activity at sub-inhibitory concentrations, reducing the minimum inhibitory concentrations (MICs) of at least one of the tested antibiotics by at least 8-fold, with three derivatives (7c, 11g, and 11i) achieving 32-fold MIC reductions at 128 μg/mL.
View Article and Find Full Text PDFDisabil Rehabil Assist Technol
September 2025
Department of Education, Fuzhou University of International Studies and Trade, Fuzhou, China.
This study explores the integration of traditional Chinese "Fu" culture into the moral education system for students with disabilities across K-12 and higher education through artificial intelligence. By leveraging soft computing to handle cultural ambiguities, it constructs an adaptive educational framework that aligns students' cognitive characteristics with curriculum demands, thereby enhancing their identification with Chinese culture. Guided by the theory of the "Second Combination," the research employs AI-powered soft computing to analyze the semantic and cognitive dimensions of "Fu" culture.
View Article and Find Full Text PDFBr J Educ Psychol
September 2025
Department of Human Development and Quantitative Methodology, University of Maryland, College Park, Maryland, USA.
Background: Relationships and interactions with peers have been related consistently to a range of motivational outcomes at school. This collection of papers has important implications for and raises interesting questions about the role that classmates play in motivating each other to engage academically. This is especially important given that the 'how' and 'why' of social influence on academic motivation has rarely been addressed in a systematic fashion.
View Article and Find Full Text PDFJ Am Acad Audiol
May 2025
*Department of Otolaryngology, Thomas Jefferson University, Philadelphia, PA.
Although approximately 80 percent of hearing loss cases are treatable with hearing aids (HAs), only one in four individuals who may benefit from them pursue them. Along with audiologists, physicians are integral parts of the hearing-health care team. Whether patients with hearing loss are more likely to pursue HA use based on the physician recommendation is unknown.
View Article and Find Full Text PDFComput Biol Med
September 2025
School of Medicine, University of Western Australia, 35 Stirling Hwy, Crawley, 6009, WA, Australia; Harry Perkins Institute of Medical Research, 5 Robin Warren Dr, Murdoch, 6150, WA, Australia; Department of Cardiology, Fiona Stanley Hospital, 11 Robin Warren Dr, Murdoch, 6150, WA, Australia. Electr
Remote Photoplethysmography (rPPG) promises to turn digital cameras into medical devices with the measurement of heart rates, oxygen saturation and the diagnosis arrhythmias already demonstrated. The face-centric nature of current rPPG techniques limits open-datasets from including subjects with clinically-relevant cardiorespiratory conditions without sharing private medical information. The neck, with few identifiable characteristics, is well suited to overcoming this limitation, as it serves as a region of interest (ROI) for pulse detection during jugular venous examination, a common clinical technique.
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