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Indigenous Peoples are experiencing the ongoing effects of colonization. This phenomenon, historical trauma (HT), helps to address the current ill-health disparity. Aim of this scoping review was to identify sources of evidence available to understand the impact of HT on Indigenous young peoples. A scoping review was conducted on available evidence-based literature. Article quality was assessed using validated quality appraisal tools. Synthesis was conducted with predefined levels of impact. Consistent with the literature, the themes and levels of impact were interrelated. Despite this, studies predominately reported a singular focus with limited discussion of protective factors. HT continues to have a profound impact on Indigenous young peoples across Canada, Australia, New Zealand, and the United States. Protective factors for HT were evident within Indigenous research designs. Future research should ensure a multilevel focus to explore intergenerational strength and how this influences culturally congruent health care.
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http://dx.doi.org/10.1177/1043659620935955 | DOI Listing |
Cien Saude Colet
August 2025
Departamento de Ciências Fisiológicas, Centro de Ciências da Saúde, Universidade Federal do Espírito Santo. Av. Marechal Campos 1468. 29040-090 Vitória ES Brasil.
Objective: to compare the effect of salt consumption on blood pressure (BP) of an indigenous and of a non-indigenous population in Brazil.
Design: the studies were carried out in the years of 1999-2004 in an urban population of Vitória (n = 1,663), the capital of Espírito Santo State, and in an indigenous population settled in a reserve of Aracruz (n = 663). Salt consumption was evaluated by a 12-hour overnight urine collect.
PLoS One
September 2025
Instituto de Ensino e Pesquisa, Hospital Sírio-Libanês, São Paulo, São Paulo, Brazil.
Background: Reinfections with SARS-CoV-2 have gained increasing relevance in the context of emerging immune-evasive variants and waning population immunity. Understanding their frequency and distribution is essential to guide public health strategies, particularly in middle-income countries. This study investigates the epidemiological patterns of SARS-CoV-2 reinfections in Espírito Santo, Brazil, using integrated notification and vaccination databases.
View Article and Find Full Text PDFMol Divers
September 2025
State Key Laboratory Basis of Xinjiang Indigenous Medicinal Plants Resource Utilization, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi, 830011, Xinjiang, China.
Aurora kinases are a group of serine/threonine kinases essential for cell mitosis, comprising Aurora A, B, and C. However, the Aurora B is overexpressed in multiple tumors and the aurone has been proved to exhibit potent inhibitory activity against Aurora B kinase by our group. The indolinone was considered as an aurone scaffold hopping analog, and the indolinone-based Aurora B inhibitor library (3577 molecules) was constructed by FBDD strategy.
View Article and Find Full Text PDFOverview: We analysed Australian Immunisation Register (AIR) data, predominantly for National Immunisation Program funded vaccines, as at 2 April 2023 for children, adolescents and adults, focusing on the calendar year 2022 and on trends from previous years. This report aims to provide comprehensive analysis and interpretation of vaccination coverage data to inform immunisation policy and programs.
Children: Fully vaccinated coverage in Australian children in 2022 was 0.
Indian J Endocrinol Metab
August 2025
Department of Physiology, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences (NEIGRIHMS), Shillong, Meghalaya, India.
Introduction: The relationship between Vitamin D (VitD) levels and cognitive function in young adults remains unclear, with conflicting results in existing literature. This study aimed to assess the prevalence of VitD deficiency and mild cognitive impairment (MCI) and to explore the correlation between serum VitD levels and cognitive functions in young indigenous adults in Meghalaya.
Methods: A hospital-based cross-sectional study was conducted in a tertiary care centre in Shillong, Meghalaya, involving 137 healthy young individuals associated with the centre.