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Article Abstract
The sessile lifestyle of plants requires accurate physiology adjustments to be able to thrive in a changing environment. Plants integrate environmental timing signals to control developmental and stress responses. Here, we identified Far1 Related Sequence (FRS) 7 and FRS12, two transcriptional repressors that accumulate in short-day conditions, as regulators of Arabidopsis glucosinolate (GSL) biosynthesis. Loss of function of FRS7 and FRS12 results in plants with increased amplitudes of diurnal expression of GSL pathway genes. Protein interaction analyses revealed that FRS7 and FRS12 recruit the NOVEL INTERACTOR OF JAZ (NINJA) to assemble a transcriptional repressor complex. Genetic and molecular evidence demonstrated that FRS7, FRS12 and NINJA jointly regulate the expression of GSL biosynthetic genes, and thus constitute a molecular mechanism that modulates specialized metabolite accumulation.
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Article Synopsis
- Most living organisms have developed systems to track environmental changes, and in plants, the circadian clock helps determine growth and flowering times based on external signals.
- Two transcription factors in Arabidopsis thaliana, FRS7 and FRS12, act as negative regulators of these timing processes, especially in short-day conditions.
- When these factors are non-functional, plants flower earlier and grow longer stems, highlighting their role in repressing the expression of key genes involved in growth and flowering regulation.