98%
921
2 minutes
20
A history of maltreatment during childhood (e.g., physical and sexual abuse, neglect) can threaten the fundamental human need to form and maintain relationships across development, which ensure safety and security. Furthermore, parental maltreatment history presents considerable risk for the emergence of disrupted parenting behaviors (i.e., contradictory communication, sexualized/role-reversed behavior, disorientation, intrusiveness/negativity, and severe withdrawal), which in turn are associated with children's social-emotional development. The purpose of the present study was to examine whether experiences of childhood maltreatment during pregnancy can predict risk for disrupted parenting behavior before the birth of the child. Given the inherent variability in parenting behaviors, we were interested in how different types or combinations of experiences of maltreatment during childhood are associated with later parenting behaviors. Data were drawn from 120 women from a longitudinal study that spanned from the third trimester of pregnancy through 3-year postpartum. In the current study, mothers' experiences of childhood maltreatment were assessed during pregnancy, and disrupted parenting behaviors were coded from videotaped mother-infant interactions 1-year postpartum. Four profiles of childhood maltreatment were identified using latent profile analysis: low exposure, high exposure, high sexual maltreatment, and high physical and emotional maltreatment. Results revealed that high exposure to multiple types of childhood maltreatment most strongly predicted later disrupted parenting behavior. Women with multiple exposures to different types of maltreatment during childhood may require more intense intervention during pregnancy to prevent risk for the development of disrupted parenting behavior.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1177/0886260520906175 | DOI Listing |
Theor Appl Genet
September 2025
Plant Breeding, Wageningen University & Research, P.O. Box 386, 6700 AJ, Wageningen, The Netherlands.
Potato bolters are caused by excision of a transposon from the StCDF1.3 allele, resulting in a somatic mutant with late maturity. Somatic mutations during vegetative propagation can lead to novel genotypes, known as sports.
View Article and Find Full Text PDFPlant Biotechnol J
September 2025
Huck Institutes of the Life Sciences, Penn State University, University Park, Pennsylvania, USA.
Black pod disease, caused by a complex of Phytophthora species, poses a severe threat to global cacao production. This study explores the use of CRISPR-Cas9 genome editing to reduce disease susceptibility in Theobroma cacao L. by targeting the TcNPR3 gene, a known negative regulator of plant defence.
View Article and Find Full Text PDFPediatr Blood Cancer
September 2025
Child Health Evaluative Sciences, Hospital for Sick Children, Toronto, Ontario, Canada.
Purpose: Children with B-acute lymphoblastic leukemia (B-ALL) treated in resource-intensive settings have a high likelihood of cure, but therapy is long, burdensome, and associated with substantial toxicities. Understanding parents' perceptions of the most disruptive and difficult aspects of B-ALL treatment is critical to future improvements in care. We aimed to understand which child side effects, chemotherapeutic agents, and aspects of leukemia care are rated difficult or disruptive by parents, and variations based on parent or child characteristics.
View Article and Find Full Text PDFJ Extracell Vesicles
September 2025
Division of Sports Medicine and Adult Reconstructive Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu, China.
Osteoarthritis (OA), the prevalent debilitating joint disorder, is accelerated by dysregulated intercellular crosstalk, yet the role of fibroblast-like synoviocyte (FLS)-derived extracellular vesicles and particles (EVPs) in disease progression remains to be elucidated. Here, integrative analysis of clinical specimens, animal models, and publicly available datasets revealed significant alterations in exosomal pathways within OA synovium. Proteomic profiling revealed distinct molecular signatures in EVPs derived from inflammatory and senescent FLSs, reflecting the pathophysiological status of their parent cells.
View Article and Find Full Text PDFFront Microbiol
August 2025
Department of Medical Laboratory Diagnostics, School of Medical Technology, Shaoyang University, Shaoyang, China.
is an environmental opportunistic fungal pathogen, which can lead to invasive aspergillosis in immunocompromised individuals, and resistant to conventional antifungual agents has become a growing concern. This study investigated the antifungal activity and the molecular antifungal mechanisms of Cinnamaldehyde (CA) against , specifically its impact on metabolic pathways and protein metabolism. In susceptibility tests, CA was found to exhibit promising antifungal activity against in both solid and liquid culture (biomass) systems, with the minimum inhibitory concentration (MIC) determined as 40-80 μg/mL.
View Article and Find Full Text PDF