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Background: Percutaneous sacroiliac (SI) screw fixation is the standard operative treatment of traumatic disruptions to the posterior pelvic ring. The technique offers good outcomes and early postoperative mobilization, which is vital in elderly patients with fragility fractures of the pelvis. While a double-screw technique has been shown to provide optimal biomechanical stability compared to a single-screw construct, anatomic variations and patient-specific characteristics may prevent the safe insertion of two SI screws. We aimed to determine whether cement augmentation of a single SI screw would provide biomechanical stability comparable to that of the double-screw technique.
Methods: Three sacroiliac screw osteosynthesis configurations were tested on 10 human cadaveric pelvis specimens: a single cannulated screw; two cannulated screws; and a single, cement-augmented cannulated screw. Displacement and stiffness of the anterior and posterior pelvic ring after fixation with each technique were measured under axial load. Results where compared using linear regression and paired t-tests.
Results: A single uncemented screw offered significantly worse stability in the anterior pelvis compared to a double-screw technique (P < 0.05) and to a single cement-augmented screw technique (P < 0.05). There was no significant difference in anterior pelvic ring stability between the single cement-augmented screw technique and the double-screw technique (P > 0.05). There was no significant difference in the stability of the posterior pelvic ring between the three techniques (P > 0.05).
Conclusions: A single cement-augmented cannulated sacroiliac screw provides biomechanical stability similar to that of a non-augmented double-screw technique in the treatment of posterior pelvic ring fractures.
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http://dx.doi.org/10.1016/j.injury.2020.01.043 | DOI Listing |
J Biomech Eng
September 2025
Oral and Maxillofacial Surgery, University Hospitals Leuven, Kapucijnenvoer 33, 3000 Leuven, Belgium.
The patient-specific mandibular reconstruction plate (PSMRP) has gained prominence for its precise adaptation to mandibular contours and reported enhanced mechanical reliability compared to the manual-bent mandibular reconstruction plate (MBMRP). Despite this, a biomechanical comparison between MBMRP and PSMRP is essential for informed clinical decision-making and advancing the field of mandibular reconstruction. Thereupon, biomechanical behavior was compared between two reconstructed mandibles with the MBMRP made of commercial pure titanium plate and the PSMRP stemmed from a common ramus reconstruction case, respectively, in physiological simulation using finite element analyses.
View Article and Find Full Text PDFOper Orthop Traumatol
September 2025
Sektion Sportorthopädie, TUM Universitätsklinikum, Ismaninger Str. 22, 81675, München, Deutschland.
Objective: Anatomical reconstruction of the posterior cruciate ligament (PCL) with suture tape augmentation to enhance primary stability.
Indications: Acute or chronic PCL ruptures, either isolated or as part of multiligamentous injuries, in cases of symptomatic instability or failure of conservative treatment.
Contraindications: Fixed posterior drawer, active infection, bony avulsion.
Eur J Cell Biol
September 2025
The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, PR China; Bioinspired Engineering and Biomechanics Center (BEBC), Xi'an Jiaotong University, Xi'an 710049, PR China. Electronic address:
Cell migration toward stiffer or softer environments (durotaxis) underlies processes from development to cancer metastasis, yet the underlying mechanism and its universality remain unclear. To resolve this, we investigated how traction forces and directional persistence dictate cell migration along stiffness gradients. We utilized tunable PEG hydrogels with stiffness gradients of 1-16 kPa and perturbed contractility (blebbistatin, oligomycin), and adhesion (vinculin mutants), in cancer cells exhibiting opposing durotactic biases.
View Article and Find Full Text PDFPLoS One
September 2025
Experimental Physics, Saarland University, Saarbrücken, Germany.
Cellular adhesion and contractility are essential for cell movement. In this study, we investigated the effects of actin stabilization on adhesion properties, contractility, and cell migration. For this, we used the recently synthesized actin stabilizer miuraenamide A (MiuA), which has been discussed as a more reliable alternative to the otherwise commonly used actin stabilizer jasplakinolide.
View Article and Find Full Text PDFArch Orthop Trauma Surg
September 2025
Department of Orthopedics and Traumatology, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey.
Introduction: Tunnel widening following anterior cruciate ligament (ACL) reconstruction remains a significant clinical concern. Polyether ether ketone (PEEK) screws offer favorable biomechanical properties and MRI compatibility; however, they lack osteoconductivity, which may contribute to tunnel widening. This study investigated whether hydroxyapatite (HA)-coated polyether ether ketone (PEEK) screws reduce tibial tunnel widening compared to uncoated PEEK screws, considering the osteoconductive properties of HA.
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