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http://dx.doi.org/10.1080/15265161.2019.1701746 | DOI Listing |
ACS Sens
September 2025
College of Chemistry, Beijing Normal University, Beijing 100875, China.
Dopamine (DA) signaling is essential for neurodevelopment and is particularly sensitive to disruption during adolescence. Protein restriction (PR) can impair DA dynamics, yet mechanistic insights remain limited due to challenges in real-time neurochemical sensing. Here, we present aptCFE, a robust implantable aptamer-based sensor fabricated via a reagent-free, 3 min electrochemical conjugation (E-conjugation) using amine-quinone chemistry.
View Article and Find Full Text PDFJMIR Rehabil Assist Technol
September 2025
Department of Computer Science, Faculty of Technology, Art and Design, OsloMet - Oslo Metropolitan University, Oslo, Norway.
Background: Over the past decade, the proportion of the world's population aged ≥65 years has grown exponentially, presenting significant challenges, such as social isolation and loneliness among this population. Assistive technologies have shown potential in enhancing the quality of life for older adults by improving their physical, cognitive, and communication abilities. Research has shown that smart televisions are user-friendly and commonly used among older adults.
View Article and Find Full Text PDFJ Craniofac Surg
September 2025
Division of Plastic and Reconstructive Surgery Medical Center, Los Angeles, CA.
Auricular reconstruction is essential for restoring facial symmetry and achieving a well-contoured, natural-appearing ear. Traditional methods using autologous costal cartilage often delay reconstruction until around age 10, when sufficient rib cartilage is available, which can pose physical and psychological challenges for pediatric patients. Porous high-density polyethylene (PHDPE) implants offer significant advantages, including the ability to perform reconstruction earlier, reduced morbidity, improved ear definition, and the possibility of a single-stage outpatient procedure.
View Article and Find Full Text PDFHum Reprod
September 2025
Division of Nutritional Sciences, Cornell University, Ithaca, NY, USA.
Study Question: Does weight loss from a hypocaloric dietary intervention improve antral follicle dynamics in women with PCOS?
Summary Answer: During a 3-month hypocaloric dietary intervention, women with PCOS who experienced clinically meaningful weight loss showed more organized antral follicle development including fewer recruitment events, but no change in the overall frequency of selection, dominance, or ovulation.
What Is Known Already: There is a spectrum of disordered antral follicle development in women with PCOS including excessive follicle recruitment and turnover, decreased frequency of selection and dominance, and failure of ovulation. Lifestyle intervention aimed at weight loss is recommended to improve metabolic health in women with PCOS yet benefits on ovarian follicle development and ovulation are unclear.
JMIR Med Inform
September 2025
College of Medical Informatics, Chongqing Medical University, 1 Yixueyuan Road, Yuzhong District, Chongqing, 400016, China, 86 13500303273.
Background: Cirrhosis is a leading cause of noncancer deaths in gastrointestinal diseases, resulting in high hospitalization and readmission rates. Early identification of high-risk patients is vital for proactive interventions and improving health care outcomes. However, the quality and integrity of real-world electronic health records (EHRs) limit their utility in developing risk assessment tools.
View Article and Find Full Text PDF