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Previous studies suggest that low-frequency repetitive Transcranial Magnetic Stimulation (rTMS) over contralateral premotor cortex (PMC) might ameliorate Focal Hand Dystonia (FHD) symptoms. In the present study behavioral and muscle activity outcomes were explored in a patient with FHD following a single and multiple sessions of rTMS. The patient's behavior was assessed on handwriting tasks, while surface EMG signals were recorded. In Experiment 1 evaluations were performed before and after one session of active and sham 1Hz rTMS over contralateral PMC. In Experiment 2, evaluations were performed before and after six sessions of the same treatment. In Experiment 1 active rTMS improved the patient's performance, although the EMG amplitude did not change. In Experiment 2, the patient showed an improvement of performance along with a decrease of 20% in the EMG amplitude. These results demonstrated that a single session of rTMS ameliorated the patient's performance, while multiple sessions were necessary to reduce muscles activity.
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http://dx.doi.org/10.1016/j.heliyon.2019.e02770 | DOI Listing |
Epilepsy Behav
September 2025
Department of Neurosurgery, Epilepsy Research Center of PLA, Xinqiao Hospital, Army Medical University, 183 Xinqiao Main Street, Shapingba District, Chongqing 400037, China. Electronic address:
Objective: Semiology-based preoperative anatomical hypotheses are necessary, yet comprehensive reports on the semiology and its correlation with central subregions in central epilepsy has still lacked. We wished to identify semiologic subgroups and their correlations with central subregions.
Methods: We retrospectively included 21 patients with central epilepsy identified by stereoelectroencephalography (sEEG).
Curr Opin Crit Care
October 2025
Infectious Diseases Unit, Azienda Ospedaliera-Universitaria of Modena, University of Modena and Reggio Emilia, Modena, Italy.
Purpose Of Review: Healthcare-associated infections (HAIs) remain a critical challenge in intensive care units (ICUs) due to the high prevalence of invasive procedures, vulnerable patient populations, and the increasing threat of antimicrobial-resistant organisms (MDROs). This review synthesizes current evidence on infection prevention and control (IPC) strategies in the ICU setting, highlighting recent findings and innovations in this evolving field, particularly in light of the impact of the COVID-19 pandemic.
Recent Findings: The review outlines ten key IPC strategies for ICUs, categorizing them into horizontal (universal) and vertical (pathogen-specific) approaches.
J Environ Manage
September 2025
Ministry of Education Key Laboratory of NSLSCS, School of Mathematical Sciences, Nanjing Normal University, Nanjing, 210023, China; School of Mathematical Sciences, Jiangsu University, Zhenjiang, 212013, Jiangsu, China.
Accurate assessment and monitoring of carbon emissions (CE) are crucial for achieving emission reduction targets and sustainable development. Among the various approaches for CE accounting, the emissions factor method has the widest scope of application. However, the lack of emission factors that can fully reflect regional characteristics limits the accuracy and effectiveness of CE accounting to a certain extent.
View Article and Find Full Text PDFACS Nano
September 2025
Departments of Ultrasound Medicine Beijing Chaoyang Hospital, Capital Medical University, North Road 8, Gongti, Chaoyang, Beijing 100020, China.
Although immune checkpoint inhibitor-based immunotherapy has shown clinical efficacy in various cancer types, its efficacy in pancreatic cancer remains limited. This limitation is primarily attributed to the dense stromal tumor microenvironment (TME) and highly immunosuppressive TME of pancreatic cancer. The dense stromal TME forms a physical barrier that severely hinders the penetration and accumulation of therapeutic agents and immune cells.
View Article and Find Full Text PDFAnn Hum Biol
December 2025
Growth and Development Department, Hospital de Pediatría J.P. Garrahan, Buenos Aires, Argentina.
Background: Prader-Willi syndrome (PWS) is a complex genetic disorder characterised by infantile hypotonia, early-onset obesity, intellectual disability, hypopigmentation, small hands and feet, short stature, hypogonadism, and distinctive facial features.
Aim: To generate and report growth curves for height, sitting height, hands and feet length for Argentine children with Prader-Willi syndrome (PWS) without growth hormone treatment.
Subjects And Methods: A total of 1174 anthropometric measures were obtained from 167 children (82 boys) aged 0-19 years attending Hospital Garrahan between 1992 and 2019.