98%
921
2 minutes
20
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899448 | PMC |
http://dx.doi.org/10.1016/j.vaccine.2019.05.027 | DOI Listing |
Pediatr Res
September 2025
Division of Developmental and Behavioral Pediatrics, Department of Pediatrics, University of Michigan Medical School, Ann Arbor, MI, USA.
Background: Children with congenital cytomegalovirus (cCMV) have a wide spectrum of possible neurodevelopmental outcomes.
Objectives: To describe neurodevelopmental (ND) Phenotypes of children with cCMV based on medical, developmental, and behavioral outcomes in childhood, and examine whether birth characteristics were associated with ND Phenotype.
Methods: Caregivers of children with cCMV (N = 242, child aged 12 months to <11 years) completed survey instruments reporting on the child's birth characteristics, reasons for cCMV testing, and present medical, developmental, and behavioral status.
World J Pediatr Congenit Heart Surg
September 2025
Congenital Heart Center, Departments of Surgery and Pediatrics, University of Florida, Gainesville, FL, USA.
This analysis evaluates the longitudinal impact of extracorporeal membrane oxygenation (ECMO) and ventricular assist device (VAD) on the progression of motor delay and cognitive delay in pediatric heart transplant recipients. The United Network for Organ Sharing Registry was queried for pediatric patients (<18 years) who received a heart transplant between 2008 and 2022 and were bridged-to-transplantation with either ECMO or VAD. Patients were further stratified based on the progression of delay status pretransplant to post-transplant.
View Article and Find Full Text PDFEpigenomics
September 2025
College of Physical Education, Yangzhou University, Yangzhou, China.
Background: Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder lacking objective biomarkers for early diagnosis. DNA methylation is a promising epigenetic marker, and machine learning offers a data-driven classification approach. However, few studies have examined whole-blood, genome-wide DNA methylation profiles for ASD diagnosis in school-aged children.
View Article and Find Full Text PDFCureus
August 2025
Pediatric Nephrology, Hospital Pediátrico, Unidade Local de Saúde de Coimbra, Coimbra, PRT.
Introduction Nephrogenic diabetes insipidus (NDI) is a rare condition caused by renal resistance to the action of antidiuretic hormone (ADH) at the level of the distal tubule, resulting in impaired urinary concentration and consequent polyuria. NDI may be hereditary, most commonly X-linked due to AVPR2 gene mutations, or acquired. Objective To characterize the clinical features, management strategies, and outcomes of patients with NDI followed at a tertiary pediatric nephrology center.
View Article and Find Full Text PDFCureus
August 2025
Faculty of Medicine, Universidad de Costa Rica, San José, CRI.
Autism spectrum disorder (ASD) is a neurodevelopmental syndrome that impacts two main areas: social communication and restrictive or repetitive behaviors. Other symptoms and comorbidities may be manifested, according to the different clinical presentations and severity levels. ASD diagnosis can be performed by two years of age; however, certain diagnostic challenges may lead to a late diagnosis and significant intervention delay.
View Article and Find Full Text PDF