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We report the first case, to our knowledge, in Italy, of a severe combined immunodeficiency patient with a persistent rotavirus infection due to a vaccine derived strain. Rotavirus was detected by enzyme immunoassays and RT-PCR in stool specimens for five months. The persistent infection was resolved after complete immune reconstitution achieved by hematopoietic stem cell transplantation. This case underlines the importance of neonatal SCID_screening.
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http://dx.doi.org/10.3390/vaccines7040185 | DOI Listing |
J Med Virol
September 2025
Department of Gynaecology, Shandong Provincial Third Hospital, Shandong University, Jinan, Shandong, China.
Persistent high-risk human papillomavirus (HPV) infection is a leading cause of cervical cancer worldwide. While prophylactic vaccines exist, many women remain at risk due to prior exposure or limited access to vaccination. Current treatments focus on ablating visible lesions but often fail to clear the virus completely.
View Article and Find Full Text PDFEnviron Microbiol
September 2025
Listeria: Biology and Infection Research Group (LisBio), Valencia, Spain.
Listeria monocytogenes is a saprophytic bacterium and a foodborne pathogen of humans and animals. Little is known about its distribution and genetic diversity across different environments within the same geographical region. We conducted a large-scale longitudinal study in southeastern Spain monitoring Listeria spp.
View Article and Find Full Text PDFActa Trop
September 2025
State Key Laboratory for Animal Disease Control and Prevention/College of Veterinary Medicine, Lanzhou University/ WOAH Reference Laboratory for Cysticercosis/ National Para-reference Laboratory for Animal Echinococcosis/Gansu Province Research Center for Basic Disciplines of Pathogen Biology/ Key L
Cystic echinococcosis (CE) and Taenia spp. infections are major zoonotic helminthiases with substantial public health and economic burdens, particularly in endemic regions. Despite their classification as neglected tropical diseases (NTDs), these tapeworm infections remain understudied in Nigeria.
View Article and Find Full Text PDFJ Ethnopharmacol
September 2025
School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, 102400, China. Electronic address:
Ethnopharmacological Relevance: Fever is a prevalent clinical symptom and is usually caused by inflammation or infection. Persistent high fever can lead to delirium, coma and convulsions, causing brain damage. Angong Niuhuang Pill (ANP), a traditional Chinese emergency medicine, has been employed in clinical practice for centuries, with well-documented antipyretic effects.
View Article and Find Full Text PDFCurr Opin Virol
September 2025
Department of Hematology, Rheumatology and Infectious Diseases, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan. Electronic address:
Human T-cell leukemia virus type I (HTLV-1) was the first human pathogenic retrovirus to be discovered. HTLV-1 induces a T-cell malignancy, adult T-cell leukemia-lymphoma (ATL), and inflammatory diseases, such as HTLV-1-associated myelopathy (HAM), HTLV-1 uveitis (HU), and HTLV-1-associated pulmonary disease (HAPD). Importantly, HTLV-1 maintains persistent infection by regulating viral gene expression and disrupting host signaling pathways - activities that are closely linked to its pathogenicity.
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