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Article Abstract

We report the first case, to our knowledge, in Italy, of a severe combined immunodeficiency patient with a persistent rotavirus infection due to a vaccine derived strain. Rotavirus was detected by enzyme immunoassays and RT-PCR in stool specimens for five months. The persistent infection was resolved after complete immune reconstitution achieved by hematopoietic stem cell transplantation. This case underlines the importance of neonatal SCID_screening.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963346PMC
http://dx.doi.org/10.3390/vaccines7040185DOI Listing

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