98%
921
2 minutes
20
Stall base and stall surface (i.e., with or without bedding) are key risk factors in cow comfort in dairy herds. In Canada, rubber mats, concrete floors, and mattresses are the most common stall bases used in tie-stall systems. Straw, wood shavings, and sand, at variable depths, are the most commonly used type of bedding. The Clegg hammer (Clegg Impact Soil Tester Hammer; Lafayette Instrument Company, Lafayette, IN) is a tool used by engineers to test the compressibility of pavement or golf course surfaces. Recently, this tool has also been used to measure the compressibility of the stall surface on freestall dairy farms. A total of 32 tie-stall dairy herds were selected in Québec to test the usefulness of the Clegg hammer as a tool to assess stall surface compressibility in tie-stall housing. This study had 2 main objectives: (1) identify the location and the number of measurements needed to obtain a stable indicator of compressibility, and (2) identify differences in the compressibility of the stall surface depending on the stall base and bedding depth. On each farm, we tested the compressibility of 10 stalls. No significant differences were found between the front and the back of the stall for the location of the Clegg hammer measures. The differences in readings of the Clegg hammer were nonsignificant after the third measure taken at the same location, meaning that 3 measures are sufficient at one location to obtain a compressibility measure. Significant differences were found among the different stall base and surface combinations tested. Rubber mats were less compressible than mattresses. When a large quantity of bedding (>7.5 cm) was added on top of rubber mats, the compressibility results were equal to those of mattresses ≥10 yr old without bedding. To appropriately test the compressibility of stall surface in tie-stall farms, we recommend measuring the compressibility of the stall base on its own and with the usual amount of bedding used on the farm. Our study establishes that both stall base and surface affect compressibility, and that a large quantity of bedding helps increase the compressibility of the bed, especially on a harder stall base.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.3168/jds.2019-16308 | DOI Listing |
Mil Med
August 2025
The Telemedicine and Advanced Technology Research Center, Frederick, MD 21702-5012, United States.
Large-scale combat operations (LSCO) will challenge the current U.S. military trauma system with high casualty volumes, prolonged evacuation timelines, and degraded logistics.
View Article and Find Full Text PDFMil Med
July 2025
Divisions of Trauma, Surgical Critical Care and Burns, Daughtry Family Department of Surgery, University of Miami Miller School of Medicine and Jackson Memorial Hospital Ryder Trauma Center, and US Army Trauma Training Center, Miami, FL 33136, United States.
Introduction: Role 2 (R2) U.S. military treatment facilities provide lifesaving far forward damage control resuscitation and surgery.
View Article and Find Full Text PDFJ Trauma Acute Care Surg
August 2025
From the Department of Orthopedics (J.M.B.), and Department of Surgery (L.C.B., L.P.), Madigan Army Medical Center, Tacoma, WA; and Joint Trauma System (C.A.S., J.D.S., J.G.), Defense Health Agency, Joint Base Fort San Houston, San Antonio, TX.
Background: The United States has been involved in ongoing combat operations since 2001, the longest period of conflict in the nation's history. This study's intent was to analyze a central Department of Defense casualty database to delineate wound distribution patterns and mechanisms of injury during the conflicts in the Middle East with a particular focus on musculoskeletal injury.
Methods: A retrospective analysis of the Military Orthopedic Trauma Registry was completed for all US service members treated for wounds in the Iraq, Afghanistan, and Syria theater of operations injured between January 1, 2001, and December 31, 2023, who were abstracted into Military Orthopedic Trauma Registry.
Exp Hematol Oncol
June 2025
Department of Molecular Pharmacology & Experimental Therapeutics, Mayo Clinic, 55905, Rochester, MN, USA.
The prognosis for women with ovarian cancer (OC) is particularly poor if resistance to platinum compounds, the mainstay of standard-of-care therapy, develops. Inhibitors of the Nudix hydrolase MuT Homolog 1 (MTH1) have previously been shown to arrest cancer cells in mitosis, increase 8-oxo-2'-deoxyguanosine (8-oxo-dG) incorporation into DNA, and selectively kill neoplastic cells while sparing normal cells. Here we explored the cytotoxic mechanism of these agents as well as their activity against platinum-resistant OC in vitro and in vivo.
View Article and Find Full Text PDFCancer Chemother Pharmacol
June 2025
Second Department of Encephalopathy, The Second Affiliated Hospital of Shaanxi University of Chinese Medicine, Xiangyang, 712046, China.
SLFN11, a DNA/RNA helicase implicated in replication stress response, has recently emerged as a pivotal determinant of chemotherapy sensitivity across multiple cancer types. The expression level of SLFN11 in various cancers is significantly positively correlated with the sensitivity of cancer cell DNA damage agents. SLFN11 exerts its chemosensitizing effects by RPA-coated single-stranded DNA (ssDNA) at stressed replication forks at stalled replication forks, thereby potentiating the cytotoxicity of platinum agents, topoisomerase inhibitors, and PARP inhibitors.
View Article and Find Full Text PDF