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Background: Cancer patients are considered the most at risk of the consequences of catheter occlusion. Therefore, nursing interventions that can effectively reduce the occlusion of peripherally inserted central catheter (PICC) lines must be identified to ensure a smooth treatment.
Objective: This study aimed to evaluate nursing interventions to minimize PICC line occlusion and make recommended measures for preventing or decreasing occlusion and abnormal extubation.
Methods: Studies about PICC occlusion that were published up to January 2017 were searched and screened in PubMed, Web of Science, Science Direct (Elsevier), EMBASE, Cochrane Library, and Chinese databases CNKI and Wanfang. Two independent reviewers screened the literature in accordance with the inclusion and exclusion criteria, assessed the quality of the included studies, and extracted the data. Further meta-analysis was performed using RevMan 5.3.
Results: Thirteen trials were included. Meta-analysis revealed that education for nurses (relative risk, 0.31; 95% confidence interval, 0.19-0.51; P < .00001) was significantly associated with PICC occlusion, whereas PICC type (relative risk, 0.60; 95% confidence interval, 0.32-1.15; P = .12) was not significantly associated with PICC occlusion. The solution to washing pipes and the PICC insertion techniques were descriptively analyzed to reach statistical significance.
Conclusion: This study determined the correlation of PICC occlusion with the nurses' knowledge and skills, PICC types, flushing liquid and methods, and insertion techniques.
Implications For Practice: The findings of this study can serve as a guide for clinical work and for developing targeted measures to reduce occlusion.
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http://dx.doi.org/10.1097/NCC.0000000000000664 | DOI Listing |
Int J Hematol
September 2025
Department of Hematology and Oncology, Asahikawa Red Cross Hospital, 1-1 Akebono-Cho, Asahikawa, Hokkaido, Japan.
Introduction: Allogeneic hematopoietic stem-cell transplantation (allo-HSCT) requires reliable vascular access for medication, transfusion, and blood sampling, which often involves painful venipuncture. This prospective study evaluated a novel dual peripherally inserted central venous catheter (PICC) technique to reduce venipuncture frequency in allo-HSCT recipients.
Methods: The study enrolled 29 allo-HSCT recipients.
Healthcare (Basel)
August 2025
Department of Anaesthesia and Perioperative Medicine, Royal Brisbane and Women's Hospital, Brisbane, QLD 4006, Australia.
Background: Peripherally inserted central catheters (PICCs) are becoming an increasingly utilised alternative to traditional central venous access devices. Their uptake, particularly among oncology patients, is due to their growing ease of access, suitability for medium-term use and perceived safety profile. However, PICCs can be a source of severe and life-threatening complications such as central line-associated bloodstream infection (CLABSI), deep vein thrombosis (DVT), pulmonary embolism (PE), malpositioning, dislodgement, and occlusion.
View Article and Find Full Text PDFJ Vasc Access
May 2025
Department of Medicine and Surgery, University of Milan-Bicocca, Monza, Italy.
Background: Needle-free connectors (NFCs) are closure systems for vascular catheters largely used because effectively reduce needlestick incidents. They are classified based on their impact on the fluid column within the catheter as (fluid displacement into the vein), (fluid displacement back from the vein into the catheter), (minimal displacement), or (equipped with additional anti-reflux valve). Each category has specific usage and clamping procedures.
View Article and Find Full Text PDFAnn Noninvasive Electrocardiol
May 2025
College of Nursing, Capital Medical University, Beijing, China.
Objective: To simulate thrombotic occlusion of catheters and develop a model for thrombotic occlusion in peripherally inserted central catheters (PICC), providing a framework for research on catheter occlusion and post-occlusion recanalization.
Methods: Following preparatory steps prior to modeling, sterile anticoagulant bovine blood was drawn and injected into the PICC. Subsequently, the catheter tip was clamped and left to stand for 72 h.
Br J Nurs
April 2025
Teleflex Incorporated, Morrisville, North Carolina, USA.
Central venous catheters (CVCs) and arterial catheters (ACs) are indispensable tools in modern healthcare, enabling life-saving therapies. However, they carry risks of complications such as bloodstream infections, thrombosis, and procedural mishaps, which impact patient safety and healthcare costs. Nurse-driven central line insertion (NDCLI) programs offer a proactive approach to address these challenges by empowering trained vascular access nurses to perform CVC and AC insertions.
View Article and Find Full Text PDF