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A 44-year-old man was admitted to our hospital due to heart failure. Transthoracic echocardiography demonstrated global hypokinesis with an ejection fraction of 25%, prominent trabeculation and deep intertrabecular recesses, and apical aneurysm with multiple thrombi (10×13 mm in the inferior wall, 15×8 mm in the anterior wall). Cardiac magnetic resonance imaging showed an increased ratio of noncompacted (NC) to compacted (C) myocardium (NC/C ratio >2.3) and apical aneurysm. Coronary angiography revealed no significant stenosis. He was therefore diagnosed with left ventricular noncompaction complicated by apical aneurysm. Four weeks after starting anticoagulation, the multiple apical thrombi disappeared without clinical signs of embolism.
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http://dx.doi.org/10.2169/internalmedicine.3489-19 | DOI Listing |
Cureus
August 2025
Medicine/Cardiology, Madigan Army Medical Center, Tacoma, USA.
Apical hypertrophic cardiomyopathy (ApHCM) is an uncommon, nonobstructive form of hypertrophic cardiomyopathy (HCM) that is associated with an increased risk of ventricular aneurysms, atrial fibrillation, heart failure, and cardiac death. In this case report, a 63-year-old male patient was found to have deeply negative T waves on electrocardiogram (EKG) during a routine preoperative evaluation in an outpatient internal medicine clinic. Imaging with echocardiography and cardiac magnetic resonance confirmed the diagnosis of ApHCM.
View Article and Find Full Text PDFCirc Heart Fail
September 2025
Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Japan.
JACC Clin Electrophysiol
August 2025
University of Rennes, Centre Hospitalier Universitaire (CHU) Rennes, INSERM, LTSI-UMR 1099, Rennes, France.
Background: Therapeutic strategies for electrical storm (ES) in patients with hypertrophic cardiomyopathy (HCM) are not well defined, yet this population is at risk for ventricular arrhythmias (VAs).
Objective: The aim of this study was to analyze acute management, in-hospital mortality, and long-term outcomes of patients with HCM experiencing ES.
Methods: This multicenter study retrospectively enrolled patients with ES complicating HCM between 2017 and 2023 in 6 tertiary centers.
JACC Case Rep
August 2025
Mount Sinai Fuster Heart Hospital, New York, New York, USA.
Background: Optimal management of cardiogenic shock (CS) after acute myocardial infarction (AMI) frequently consists of inotropes and consideration of a mechanical circulatory support. However, this initial approach may be counterproductive in some CS phenotypes.
Case Summary: A 75-year-old female presented with AMI of the left anterior descending artery and underwent successful revascularization.
Int J Cardiovasc Imaging
September 2025
Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Via Giustiniani 2, Padova, 35128, Italy.
Hypertrophic cardiomyopathy (HCM) is a myocardial disease characterized by unexplained left ventricular hypertrophy, myocyte disarray, and interstitial fibrosis. A dynamic left ventricular outflow tract obstruction is present in approximately two-thirds of patients, and is typically associated with systolic anterior motion of the mitral valve. A distinct subgroup exhibits mid-ventricular obstruction, frequently associated with apical aneurysm and a higher risk of sudden cardiac death.
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