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Purpose Of Review: Upper gastrointestinal bleeding (UGIB) is a common and life-threatening condition in the United States and worldwide.
Recent Findings: There have been several exciting recent advances in the endoscopic management of UGIB. One such advance is the recent approval of Hemospray by US Food and Drug Administration in May 2018. Another one is the emerging role of video capsule endoscopy as a triage and localization tool for UGIB patients. Finally, the development of new reversal agents for antithrombotic medications is an important advance in the management of life-threatening upper gastrointestinal bleed.
Summary: In this article, we will broadly review the management of nonvariceal UGIB, focusing primarily on the data addressing these new advances.
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http://dx.doi.org/10.1097/MOG.0000000000000582 | DOI Listing |
Adv Sci (Weinh)
September 2025
Postgraduate training base Alliance of Wenzhou Medical University (Zhejiang Cancer Hospital), Hangzhou, 310022, China.
Asthma is a chronic inflammatory respiratory disease influenced by genetic and environmental factors. Emerging evidence suggests that microplastics and nanoplastics (NPs) pose significant health risks. When inhaled, these tiny particles can accumulate in the lungs, triggering inflammation, oxidative stress, and other disruptions in pulmonary function.
View Article and Find Full Text PDFJ Vasc Surg Cases Innov Tech
December 2025
Department of Vascular Surgery, Baptish Health, Birmingham, AL.
Subclavian artery-esophageal fistula is a rare but potentially fatal vascular anomaly. Inherent to Downs syndrome, trisomy 21 presents with a variety of rare cardiac and vascular anomalies. Subclavian-esophageal fistulae are rare and often fatal complications of a right-sided aortic arch.
View Article and Find Full Text PDFCureus
August 2025
Department of Medical Services, Alembic Pharmaceuticals Limited, Mumbai, IND.
Introduction Upper respiratory tract infections (URTIs) are commonly encountered in primary care. Azithromycin has emerged as a preferred therapy for URTIs due to its once-daily dosing, low resistance risk, and favorable gastrointestinal tolerability. This study evaluated the real-world effectiveness and safety of azithromycin (500 mg/day) in moderate to severe acute URTIs.
View Article and Find Full Text PDFCureus
August 2025
Internal Medicine, Al Jahra Hospital, Al Jahra, KWT.
Carcinoembryonic antigen (CEA) is a commonly used tumor marker, primarily for the surveillance of colorectal and other gastrointestinal malignancies. However, its diagnostic specificity is limited, as CEA levels may be elevated in several benign conditions. This case report aims to highlight the potential diagnostic confusion and psychological distress caused by incidental CEA elevation in asymptomatic individuals when tested outside of an appropriate clinical context.
View Article and Find Full Text PDFCureus
August 2025
Gastroenterology, School of Digestive and Liver Diseases, Institute of Post-Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial Hospital, Kolkata, IND.
Background and objectives Esophageal motility disorders (EMDs) are a major cause of non‑obstructive dysphagia. However, regional data from eastern India are limited. This study aims to describe the spectrum of EMDs in patients with non‑obstructive dysphagia using high‑resolution manometry (HRM) at a tertiary care center in eastern India, and to compare clinical symptoms, and endoscopic and barium findings in patients with achalasia versus non‑achalasia.
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