Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
A multimeric MRI contrast agent based on the closo-borane motif is reported. Twelve copies of a modified AAZTA chelate with an alkyne end group are appended on an azide-functionalized closo-borane motif using Cu(i) catalyzed click chemistry. The presence of two water molecules on the Gd-bound AAZTA chelate results in high relaxivity for the closomer in vitro/in vivo.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/c9cc05383b | DOI Listing |
Publication Analysis
Top Keywords
multimeric mri
8
mri contrast
8
contrast agent
8
agent based
8
based closo-borane
8
modified aazta
8
closo-borane motif
8
aazta chelate
8
closo-borane scaffold
4
scaffold bearing
4