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Objective: The aim of this clinical trial was to assess the effect of resin infiltration on the progression of proximal caries lesions.
Subjects And Methods: Forty-one patients, aged between 15 and 33 years, with 2 or more non-cavitated proximal caries lesions were included. In 41 of the adolescent and young adults, 45 pairs of proximal lesions with radiological extension into the inner and outer half of the enamel, or into the outer third of the dentin, were randomly allocated to the test groups (resin infiltration application + fluoridated toothpaste and flossing use) or to the control group (fluoridated toothpaste and flossing use). Standardized geometrically aligned digital bitewing radiographs were obtained using individual biting holders. The radiographic progression of the lesions was assessed after 1 year by digital-subtraction radiography. The McNemar test was used for statistical analysis.
Results: In the test group 1/45 of the lesions (2.2%) and in the control group 9/45 of the lesions (20%) showed progression. The caries progression rate of the control group was significantly higher than that of the test group (p < 0.05).
Conclusions: Resin infiltration of proximal caries lesions is effective in reducing progression of the lesion.
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http://dx.doi.org/10.1159/000503053 | DOI Listing |
J Dent
September 2025
State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, National Clinical Research Center for Oral Diseases, Sichuan University, Chengdu 610041, China; Department of Operative Dentistry and Endodontics, West China School of Stomatology, Sichuan University, Chengdu 610041, China. E
Objectives: The aim of this study is to explore the specific application scenarios of quantitative light-induced fluorescence (QLF) in the detection and treatment of early caries, so as to provide more evidence for the clinical application of QLF.
Methods: (1) The accuracy of QLF in detecting the lesion depth of early caries was evaluated by combining transverse microradiography (TMR) and spectrophotometer analysis (n=6). (2) Resin infiltration therapy was used as a representative method for the treatment of early caries to evaluate the ability of QLF in assessing the therapeutic effect on early caries (n=6).
ACS Appl Mater Interfaces
September 2025
Engineering Ceramic Center, Korea Institute of Ceramic Engineering & Technology (KICET), Icheon 17303, Republic of Korea.
With the rapid advancement of space technologies, ensuring the reliable performance of electronic systems in extreme space environments has become increasingly critical. However, conventional polymeric materials used in electronic device packaging suffer from insufficient neutron shielding capability and poor thermal stability, requiring improved effectiveness in protecting sensitive components from high-energy radiation and drastic temperature fluctuations. In this study, we report a novel multilayered composite consisting of boron nitride microbridle (BNMR) and epoxy resin.
View Article and Find Full Text PDFJ Appl Oral Sci
September 2025
Universidade de São Paulo, Faculdade de Odontologia, Departamento de Dentística, São Paulo, Brasil.
Background: Considering that a single passive application of hydrochloric acid (HCl) as a resin infiltration pretreatment can remove between 20 and 45 µm of enamel and cause etching that extends up to 2 mm beyond the white spot lesions (WSLs), it is plausible that its repeated and active applications could result in a greater amount of dental tissue being removed.
Objective: To evaluate the enamel surface loss and micromorphology after etching with 15% HCl using two application methods (passive-P and active-A) and varying numbers of applications (C-placebo - 120 s; 1x HCl - 120 s; 2x HCl - 120 s + 120 s; 3x HCl - 120 s + 120 s + 120 s).
Methodology: Bovine incisors with ≤0.
Mater Today Bio
October 2025
Hepatobiliary Center, The First Affiliated Hospital of Nanjing Medical University, Key Laboratory of Liver Transplantation, Chinese Academy of Medical Sciences, NHC Key Laboratory of Living Donor Liver Transplantation, Nanjing, China.
Transarterial radioembolization (TARE) is a key therapy for hepatocellular carcinoma (HCC) management and downstaging. While Y microspheres (glass/resin) are widely used, their clinical application is limited by complexity, short half-life, and high costs. Thus, novel radionuclide microspheres are crucial.
View Article and Find Full Text PDFEur J Oral Sci
August 2025
Faculty of Dentistry, Department of Prosthodontics, Selcuk University, Konya, Turkey.
This study evaluated the influence of femtosecond (fs) laser micromachining and hydrofluoric acid (HF)-etching on the surface roughness (Ra) and resin bond strength of restorative materials. The study used 120 rectangular-shaped specimens from four computer-aided design/manufacturing (CAD/CAM) blocks (lithium-disilicate glass-ceramic [LDS; e.max CAD], leucite-reinforced glass-ceramic [LGC; Empress CAD], zirconia-reinforced lithium-silicate [ZLS; Vita Suprinity], and polymer-infiltrated-ceramic-network [PICN; Vita Enamic]) and divided them into three subgroups based on the surface treatments applied: Control, HF-etching (HF), and fs-laser irradiation (FS).
View Article and Find Full Text PDF