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Mono- and disubstituted 4-CF β-lactams at the C-3 position have been obtained stereoselectively under basic conditions. A wide range of function such as alcohols, alkyls, aryls, esters, and double and triple bonds have been introduced.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691124 | PMC |
http://dx.doi.org/10.3389/fchem.2019.00526 | DOI Listing |
Science
August 2025
Department of Chemistry, Engineering Research Center of Advanced Rare Earth Materials (Ministry of Education), Tsinghua University, Beijing, P. R. China.
Determining the atomic structure of nanoparticles (NPs) is critical for understanding their structural evolution and properties. However, controlling the growth of multiply-twinned metal NPs remains challenging because of numerous competing pathways. In this work, we report the synthesis of two giant silver icosahedral nanoclusters, [Ag(C≡CR1)] and [AgCl(C≡CR2)] (Ag and Ag, R1 =3,4,5-FCH and R2 = 4-CFCH), achieved through ligand engineering and kinetic control.
View Article and Find Full Text PDFJ Am Chem Soc
August 2025
Caudill Laboratories, Department of Chemistry, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-3290, United States.
Silyl palladium cations (RP)Pd-SiR catalyze the ring opening, C-C bond forming, and functionalization of 5- and 6-membered cyclic allyl ethers with -silyl nucleophiles. Conditions for high regio-control are achieved by adjustments in the phosphine electronics, with the identity of the 2-substituent also influencing the functionalization location in unsymmetrical furans. Allyl alcohols are obtained with a regio-preference for terminal addition with unsubstituted ethers with -products being obtained with XantPhos and - with (4-CF-Ar) ligation.
View Article and Find Full Text PDFInorg Chem
August 2025
Physikalische Organische Chemie, Technische Universität Dresden, Dresden 01069, Germany.
Five novel square-planar platinum(II) complexes with electron-deficient bis(3-(trifluoromethyl)-pyrazolyl)-borate auxiliary ligands were synthesized in yields ranging from 31% to 76%. The complexes feature cyclometalating C^C*-ligands based on phenyl imidazopyridines with different substituents (H, 3-Me, 4-Me, 4-EtO, and 4-CFO). All five complexes emit light in the green-blue region with photoluminescence quantum yields between 32% and 56% (2 wt % in PMMA).
View Article and Find Full Text PDFRSC Med Chem
May 2025
University of Pisa, Department of Chemistry and Industrial Chemistry Via G. Moruzzi 13 I-56124 Pisa Italy https://people.unipi.it/fabio_marchetti/.
The new diiron complex [FeCp(CO){PhP(4-CHCOH)}(μ-CO){μ-CNMe(Cy)}]CFSO, [2]CFSO (Cp = η-CH, Cy = CH), was synthesized with a 92% yield from a tricarbonyl precursor and 4-(diphenylphosphanyl)benzoic acid. The carboxylic acid group in [2] was exploited for bio-conjugation with flurbiprofen and chlorambucil through esterification procedures, affording complexes [3-4]CFSO (36-55% yields). Comprehensive characterization of the products was achieved using IR, multinuclear NMR spectroscopy and mass spectrometry.
View Article and Find Full Text PDFChemSusChem
July 2025
Frontier Institute of Science and Technology, Interdisciplinary Research Center of Frontier Science and Technology, State Key Laboratory of Electrical Insulation and Power Equipment, MOE Key Laboratory for Nonequilibrium Synthesis and Modulation of Condensed Matter, Xi'an Key Laboratory of Electroni
Though there are many synthetic iron-sulfur clusters that have been reported to show catalytic activity mimicking the natural cofactors in metalloenzymes, the influence of the spin state on the catalytic property is seldom touched. Here, a disulfide-bridged triiron(II) complex is shown, namely [Fe(Sip)][CFSO] (Fe(Sip), HSip = sulfanylpropyliminomethyl-pyridine), can efficiently electrocatalyze water oxidation with a turnover frequency of 932 s and Faraday efficiency of 86%, better than many iron-based catalysts. More importantly, the terminal low-spin (S = 0) iron(II) sites possessing a N4S2 first coordination environment, along with the synergetic catalysis of ligands, play a crucial role in the catalytic process.
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