Direct Access to Substituted 4-CF β-Lactams at the C-3 Position.

Front Chem

Faculté de Pharmacie, UMR 8076 CNRS, BioCIS, University of Paris-Sud, Univ. Paris-Saclay, Châtenay-Malabry, France.

Published: August 2019


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Article Abstract

Mono- and disubstituted 4-CF β-lactams at the C-3 position have been obtained stereoselectively under basic conditions. A wide range of function such as alcohols, alkyls, aryls, esters, and double and triple bonds have been introduced.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691124PMC
http://dx.doi.org/10.3389/fchem.2019.00526DOI Listing

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