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Our work exhibits how previous projects on the Active and Healthy Ageing field have advanced to the conception of CAPTAIN, a radically new approach towards increased end-user acceptance. The goal is to create intuitive technology that does not require specific skills for interaction and blends in with real life. CAPTAIN will be co-designed by all types of stakeholders, including older adults, involved in all stages, from the initial design to delivery of the final system.
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http://dx.doi.org/10.3233/SHTI190606 | DOI Listing |
Geroscience
September 2025
Department of Urology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
This study aims to investigate the predictive value of combined phenotypic age and phenotypic age acceleration (PhenoAgeAccel) for benign prostatic hyperplasia (BPH) and develop a machine learning-based risk prediction model to inform precision prevention and clinical management strategies. The study analyzed data from 784 male participants in the US National Health and Nutrition Examination Survey (NHANES, 2001-2008). Phenotypic age was derived from chronological age and nine serum biomarkers.
View Article and Find Full Text PDFAesthetic Plast Surg
September 2025
Department of Plastic and Cosmetic Surgery, Tongji Hospital, School of Medicine, Tongji University, No.389 Xincun Road, Shanghai, 200092, China.
Background: The integration of digital tools in aesthetic medicine has enhanced the precision of facial feature analysis. Using concepts like the Golden Ratio, these technologies enable more objective assessments of facial proportions and symmetry. The beauty scanner-face analyzer (BS-FA) app offers a digital approach to evaluate geometric proportions and facial alignment, providing valuable data for preoperative planning in plastic surgery and aesthetic treatments.
View Article and Find Full Text PDFJ Safety Res
September 2025
Vehicle Safety, Mechanics and Maritime Sciences, Chalmers University of Technology, SE 412 96 Gothenburg, Sweden.
Introduction: While previous research has focused on drivers' visual behaviors during normal driving, few studies have explored how age-related decline affects driver reactions in collisions. This study bridges this gap by investigating aging effects on driver responses in urban car-to-cyclist intersection scenarios.
Method: Twenty-four licensed drivers, younger (mean age 35.
Transplant Cell Ther
September 2025
Department of Hematology, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China; Zhejiang Provincial Clinical Research Center for Hematological disorders, Hangzhou, China; Zhejiang Key Laboratory for Precision Diagnosis and Treatment of Hematological Maligancies, Han
Background: Haploidentical hematopoietic stem cell transplantation (haplo-HSCT) offers curative potential for hematologic malignancies but is often limited by high incidences of graft-versus-host disease (GVHD), delayed engraftment, and transplant-related mortality-especially when donors are aged ≥40 years. Umbilical cord blood (UCB) infusion may mitigate these risks by promoting immune tolerance and hematopoietic recovery. However, the efficacy of this strategy in the context of older donors remains insufficiently studied.
View Article and Find Full Text PDFAnn N Y Acad Sci
September 2025
Department of Psychiatry, University of California San Diego, La Jolla, California, USA.
The current study aimed to evaluate specific mechanisms of interventions to improve loneliness among older adults. EMBASE, MEDLINE, and PsycINFO databases were searched for articles published through June 2024. We selected randomized controlled trials (RCTs) that sought to improve loneliness in older adults, were published in English, and used previously published measures to assess loneliness.
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