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Context: Enhanced recovery after surgery (ERAS) aims to improve surgical outcomes by integrating evidence-based practices across preoperative, intraoperative, and postoperative care. Data in electronic medical records (EMRs) provide insight on how ERAS is implemented and its impact on surgical outcomes. Because ERAS is a multimodal pathway provided by multiple physicians and health care providers over time, identifying ERAS cases in EMRs is not a trivial task. To better understand how EMRs can be used to study ERAS, we describe our experience with using current methodologies and the development and rationale of a new method for retrospectively identifying ERAS cases in EMRs.
Case Description: Using EMR data from surgical departments at the University of North Carolina at Chapel Hill, we first identified ERAS cases using a protocol-based method, using basic information including the date of ERAS implementation, surgical procedure and date, and primary surgeon. We further examined two operational flags in the EMRs, a nursing order and a case request for OR order. Wide variation between the methods compelled us to consult with ERAS surgical staff and explore the EMRs to develop a more refined method for identifying ERAS cases.
Method: We developed a two-step method, with the first step based on the protocol definition and the second step based on an ERAS-specific medication definition. To test our method, we randomly sampled 150 general, gynecological, and urologic surgeries performed between January 1, 2016 and March 30, 2017. Surgical cases were classified as ERAS or not using the protocol definition, nursing order, case request for OR order, and our two-step method. To assess the accuracy of each method, two independent reviewers assessed the charts to determine whether cases were ERAS.
Findings: Of the 150 charts reviewed, 74 were ERAS cases. The protocol only method and nursing order flag performed similarly, correctly identifying 74 percent and 73 percent of true ERAS cases, respectively. The case request for OR order flag performed less well, correctly identifying only 44 percent of the true ERAS cases. Our two-step method performed well, correctly identifying 98 percent of true ERAS cases.
Conclusion: ERAS pathways are complex, making study of them from EMRs difficult. Current strategies for doing so are relatively easy to implement, but unreliable. We have developed a reproducible and observable ERAS computational phenotype that identifies ERAS cases reliably. This is a step forward in using the richness of EMR data to study ERAS implementation, efficacy, and how they can contribute to surgical care improvement.
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http://dx.doi.org/10.5334/egems.304 | DOI Listing |
J Robot Surg
September 2025
Department of General Surgery, Giglio Hospital Foundation, Cefalù, Italy.
The ongoing debate regarding comparative outcomes between robotic (RRYGB) and laparoscopic (LRYGB) Roux-en-Y gastric bypass necessitates large-scale, longitudinal analysis. This PRISMA-compliant meta-analysis represents the most comprehensive evaluation to date, synthesizing data from 42 high-quality comparative studies (2000-2025) encompassing an initial screening population of 482,915 procedures. After rigorous selection, our final analysis included 38,647 patients from 27 countries, offering unprecedented geographical and temporal granularity.
View Article and Find Full Text PDFBlood Adv
September 2025
Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking, Tianjin, China.
Monoclonal gammopathy (MG) in chronic lymphocytic leukemia (CLL) portends heterogeneous outcomes, yet its molecular drivers and therapeutic implications remain undefined. In this retrospective analysis of 2,075 CLL patients (1999-2024), MG was detected in 18.47% cases, with IgM (8.
View Article and Find Full Text PDFFront Microbiol
August 2025
Public Health Ontario, Toronto, ON, Canada.
Background And Aim: Pneumococcal conjugate vaccines (PCVs) have significantly reduced pediatric invasive pneumococcal disease (IPD). However, vaccine escape variants, the emergence of non-vaccine serotypes (NVTs), and antimicrobial resistance (AMR) remain ongoing concerns. We aimed to characterize long-term trends in serotype distribution, lineage composition, and AMR patterns among pediatric IPD cases following PCV introduction in two major Canadian urban centers: Calgary, Alberta, and Toronto, Ontario.
View Article and Find Full Text PDFFront Surg
August 2025
Department of General Surgery, The Affiliated Suqian Hospital of Xuzhou Medical University, Suqian, Jiangsu, China.
Objective: To evaluate the safety and efficacy of a modified Enhanced Recovery After Surgery (ERAS) protocol integrated with laparoscopic repair for incarcerated inguinal hernia, comparing outcomes with conventional open surgery.
Methods: This single-center retrospective cohort study (2019-2024) included 200 patients with incarcerated inguinal hernia. These patients were assigned to the laparoscopy group or the open group (in a 1:1 ratio).
Ann Afr Med
August 2025
Department of Surgical Gastroenterology and GI Oncology, Indraprastha Apollo Hospitals, New Delhi, India.
Background: Intestinal obstruction remains a common surgical emergency associated with considerable morbidity and mortality, especially in low- and middle-income countries. The evolving epidemiology, emergence of postoperative adhesions as a leading cause, and adoption of modern surgical practices necessitate updated real-world analyses.
Materials And Methods: A retrospective study was conducted on 200 patients who underwent surgical management for intestinal obstruction at Indraprastha Apollo Hospitals, New Delhi, India, between January 2018 and December 2023.