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With the rapid development of material science, more and more workpieces, especially workpieces with complex curved surfaces, are being made of composite materials. Robotic non-destructive testing (NDT) systems for complex curved surface composite material parts are being used more and more. Despite the emergence of such flexible NDT systems, the detection of semi-enclosed parts is also a challenge for robotic NDT systems. In order to overcome the problem, this paper establishes an NDT solution for semi-enclosed workpieces based on a dual-robot system of synchronous motion, in which an extension arm is installed on one of the robots and presents a trajectory planning method that always ensures the extension arm is parallel to the rotary axis of a semi-enclosed workpiece and that the ultrasonic probes are perpendicular to the workpiece surface. Trajectory analysis experiments and ultrasonic NDT experiments utilizing the optimal water path distance determined by simulation result of multi-Gaussian beam model for two types of semi-enclosed workpieces are performed with the dual-robot NDT system. Experimental results prove that the dual-robot NDT scheme functions well and the planned trajectories are correct. All the hole-shaped artificial defects with diameters ≥3 mm are detected by using 2.25 MHz ultrasonic probes through the transmission testing method. Vivid 3D C-scan image of a small diameter cylindrical workpiece based on the testing result is provided for convenience of observation.
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http://dx.doi.org/10.3390/s19153359 | DOI Listing |
Nat Rev Nephrol
September 2025
Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden.
Long coronavirus disease (COVID) - commonly defined as symptoms and/or long-term effects that persist for at least 3 months after acute infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and cannot be explained by an alternative diagnosis - is a complex, multifaceted and heterogeneous disease that affects many organ systems, including the kidney. COVID-19 can cause acute kidney injury, and several studies have reported an increased risk of chronic kidney disease (CKD) following COVID-19, suggesting that CKD can be a manifestation of long COVID. Furthermore, patients with CKD are at an increased risk of severe COVID-19 and of long COVID.
View Article and Find Full Text PDFNephrol Dial Transplant
September 2025
Department of Nephrology, Capital Medical University Electric Teaching Hospital, Beijing, China.
Background: Renal fibrosis is a common pathological feature of chronic kidney disease (CKD), but its underlying mechanisms remain incompletely understood. Our previous study demonstrated that insulin-like growth factor-binding protein 5 (IGFBP-5) promotes glycolytic reprogramming in vascular endothelial cells (ECs) and exacerbates renal inflammation in diabetic kidney disease (DKD).
Methods: Human renal proximal tubular epithelial cells (HK-2) and human umbilical vein endothelial cells (HUVECs) were used.
Sci Rep
August 2025
Department of Solid State Physics, Faculty of Physics and Applied Informatics, University of Łódź, Łódź, Poland.
The growing use of advanced composites in critical applications demands reliable, non-destructive testing. Traditional techniques often detect only large defects, missing subtle local property changes that can precede major failures. Microwave spectroscopy offers a promising alternative, probing both structural and dielectric properties with high sensitivity.
View Article and Find Full Text PDFNephrol Dial Transplant
August 2025
Division of Nephrology, Richard L. Roudebush VA Medical Center, Indianapolis Indiana University School of Medicine, Indianapolis, USA.
Background: The CONFIDENCE (COmbinatioN effect of FInerenone anD EmpaglifloziN in participants with CKD and type 2 diabetes using a UACR Endpoint) trial investigated the safety and efficacy of simultaneously initiating finerenone and empagliflozin for patients with chronic kidney disease (CKD) and type 2 diabetes. This prespecified analysis aimed to determine if the predicted risk of kidney disease progression, based on KDIGO risk categories, influenced the benefits and safety of this combination therapy.
Methods: The double-blind, double-dummy trial randomized 818 adults with CKD and type 2 diabetes [urine albumin-creatinine ratio (UACR) ≥100 to <5000 mg/g] to receive once-daily finerenone plus empagliflozin, finerenone alone or empagliflozin alone, all in addition to a renin-angiotensin system inhibitor.
Nephrol Dial Transplant
August 2025
ERA Registry, Department of Medical Informatics, Amsterdam UMC - location University of Amsterdam, Amsterdam, The Netherlands.
Background: Home dialysis therapies could offer benefits to individuals undergoing dialysis. This study examines trends of home dialysis, including home haemodialysis (HHD) and peritoneal dialysis (PD) across European countries from 2012 to 2021, and evaluates transitions between home dialysis and other kidney replacement therapies (KRT).
Methods: Data from adult patients undergoing KRT in 13 European countries were obtained from the European Renal Association (ERA) Registry.