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Isothermal amplification of specific DNA molecules inside giant unilamellar vesicles. | LitMetric

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Article Abstract

An isothermal amplification circuit for specific DNA molecules was implemented in giant unilamellar vesicles. Using this circuit, over 5000-fold amplification of output DNAs was achieved, and the amplification behaviour depended on the concentration of input signal DNAs in a cell-sized compartment. Moreover, initiation of the amplification by photo-stimulation was demonstrated.

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http://dx.doi.org/10.1039/c9cc03277kDOI Listing

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