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http://dx.doi.org/10.3988/jcn.2019.15.3.410 | DOI Listing |
Jpn J Ophthalmol
August 2025
Beijing Key Laboratory of Ophthalmology and Visual Sciences, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, No. 1, Dong Jiao Min Xiang Street, Dongcheng District, Beijing, 100730, China.
Purpose: To compare the clinical and neuroimaging phenotypes in Chinese patients with congenital fibrosis of extraocular muscles (CFEOM) harboring KIF21A versus TUBB3 variants.
Study Design: Retrospective, observational case series.
Methods: A retrospective review of 37 CFEOM patients harboring mutations of KIF21A (n = 25) and TUBB3 (n = 12) with clinical examinations was performed.
Cureus
July 2025
General Practice, General Hospital, Umunze, NGA.
Myxopapillary ependymomas (MPEs) are rare, slow-growing spinal tumors that arise from the filum terminale and are classified as World Health Organization (WHO) Grade 2 tumors. They typically present with features of lower spinal cord or cauda equina compression, such as radiculopathy, limb weakness, or sphincter dysfunction. Presentation with features of increased intracranial pressure (IIP) is rare and has been reported in a few isolated cases.
View Article and Find Full Text PDFMil Med
July 2025
Frederick Primary Care Associates, Woodsboro, MD 21798, United States.
Isolated palsy of cranial nerve VI, also known as the abducens nerve, is a condition rarely seen in the obstetric population; however, there is a growing body of literature that suggests an association with pre-eclampsia and hypertensive disorders of pregnancy. We present the sixteenth case documenting this association involving a 30-year-old G1 admitted for induction of labor at 39 weeks gestational age (WGA) subsequently diagnosed with pre-eclampsia with severe features and, after an otherwise uncomplicated vaginal delivery, developed an isolated abducens nerve palsy. While similar cases reviewed in the current body of literature document self-resolution of the palsy, a thorough workup is warranted because of other potentially malignant causes for this presentation.
View Article and Find Full Text PDFOtolaryngol Pol
July 2025
Department of Pediatric Otolaryngology, Medical University of Warsaw, Warsaw, Poland.
<b>Introduction:</b> Serious intracranial complications of acute mastoiditis seem to be reduced due to vaccine prophylaxis and antibiotics, but recently, after the COVID-19 era, we observe its significant growth.<b>Aim:</b> Due to this observed growth, especially regarding central venous thrombosis, we decided to investigate the patterns of infections within our patients.<b>Materials and methods:</b> We retrospectively analyzed patients hospitalized in our clinic in the years 2018-2022 with the diagnosis of acute mastoiditis.
View Article and Find Full Text PDFRadiol Case Rep
September 2025
Faculty of Medicine and Pharmacy, Mohammed I University, Oujda, Morocco.
Isolated abducens nerve palsy is an uncommon yet clinically significant manifestation of temporal bone fracture, often following blunt head trauma. We report the case of a 52-year-old woman who sustained a right-sided head injury after a domestic fall under the influence of alcohol. She presented with diplopia, vertigo, and right-sided conductive hearing loss.
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