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Visual working memory temporarily represents a continuous stream of task-relevant objects as we move through our environment performing tasks. Previous work has identified candidate neural mechanisms of visual working memory storage; however, we do not know which of these mechanisms enable the storage of objects as we sequentially encounter them in our environment. Here, we measured the contralateral delay activity (CDA) and lateralized alpha oscillations as human subjects were shown a series of objects that they needed to remember. The amplitude of CDA increased following the presentation of each to-be-remembered object, reaching asymptote at about three to four objects. In contrast, the concurrently measured lateralized alpha power remained constant with each additional object. Our results suggest that the CDA indexes the storage of objects in visual working memory, whereas lateralized alpha suppression indexes the focusing of attention on the to-be-remembered objects.
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http://dx.doi.org/10.1162/jocn_a_01446 | DOI Listing |
JMIR Cancer
September 2025
iCARE Secure Data Environment & Digital Collaboration Space, NIHR Imperial Biomedical Research Centre, London, United Kingdom.
Background: Electronic health records (EHRs) are a cornerstone of modern health care delivery, but their current configuration often fragments information across systems, impeding timely and effective clinical decision-making. In gynecological oncology, where care involves complex, multidisciplinary coordination, these limitations can significantly impact the quality and efficiency of patient management. Few studies have examined how EHR systems support clinical decision-making from the perspective of end users.
View Article and Find Full Text PDFPLoS Comput Biol
September 2025
Sussex Neuroscience, School of Life Sciences, University of Sussex, Brighton, United Kingdom.
Individually foraging ants use egocentric views as a dominant navigation strategy for learning and retracing routes. Evidence suggests that route retracing can be achieved by algorithms which use views as 'visual compasses', where individuals choose the heading that leads to the most familiar visual scene when compared to route memories. However, such a mechanism does not naturally lead to route approach, and alternative strategies are required to enable convergence when off-route and for correcting on-route divergence.
View Article and Find Full Text PDFPLoS Comput Biol
September 2025
Faculty of Science, Cognitive and Systems Neuroscience Group, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam, the Netherlands.
Predictive coding (PC) proposes that our brains work as an inference machine, generating an internal model of the world and minimizing predictions errors (i.e., differences between external sensory evidence and internal prediction signals).
View Article and Find Full Text PDFPLoS One
September 2025
Shenzhen University Institute for Advanced Study, Shenzhen, Guangdong, China.
Trichophyton rubrum, a dermatophyte, demonstrates a notable ability to form mature biofilms on skin and associated surfaces, strengthening its resistance to antifungal agents. This characteristic poses intricate challenges in dermatological research and therapeutic strategies, underscoring the need for innovative approaches to effectively manage fungal infections. This work assessed the impact of the anti-biofilm enzymes, i.
View Article and Find Full Text PDFCereb Cortex
August 2025
School of Psychology, University of Surrey, Stag Hill, Guildford, Surrey, GU2 7XH, United Kingdom.
Alpha oscillations have been implicated in the maintenance of working memory representations. Notably, when memorised content is spatially lateralised, the power of posterior alpha activity exhibits corresponding lateralisation during the retention interval, consistent with the retinotopic organisation of the visual cortex. Beyond power, alpha frequency has also been linked to memory performan ce, with faster alpha rhythms associated with enhanced retention.
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