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Established procedures for mass casualty decontamination involve the deployment of equipment for showering with water (such as the ladder pipe system [LPS] and technical decontamination [TD]). This necessarily introduces a short, but critical delay. The incorporation of dry decontamination to the incident response process offers the potential to establish a more rapid and timely intervention. To investigate the effectiveness of various dry (DD) and wet decontamination strategies for removing a chemical warfare simulant (methyl salicylate; MS) from the hair and skin of human volunteers. The simulant was applied to volunteers via whole body exposure to an aerosol. Three decontamination protocols (dry, LPS and technical decontamination) were applied, singly and in various combinations. The efficacy of the protocols was evaluated by fluorescent photography and analysis of residual MS from skin/hair swabs, decontamination materials and air samples. Dry decontamination was effective, with the greatest reduction in skin and hair contamination arising from the "Triple Protocol" (DD+LPS+TD). Secondary hazards associated with contaminated individuals and equipment decreased as the number of decontamination procedures increased. In particular, dry decontamination reduced the potential contact and inhalation hazard arising from used washcloths, towels and vapor within the TD units. The introduction of dry decontamination prior to wet forms of decontamination offers a simple strategy to initiate treatment at a much earlier opportunity, with a corresponding improvement in clinical outcomes and substantial reduction of secondary hazards associated with operational processes.
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http://dx.doi.org/10.1080/10903127.2019.1636912 | DOI Listing |
Biosaf Health
August 2025
Department of Microbiology and Immunology, University of Nevada, Reno School of Medicine, MS320, Reno 89557 Nevada, United States of America.
The role of personal protective equipment (PPE) in protecting against exposure to infectious agents and toxic chemicals is well-established. However, the global surge in PPE demand during the pandemic exposed challenges, including shortages and environmental impacts from disposable waste. Developing effective, scalable, and sustainable decontamination methods for the reuse of PPE is essential.
View Article and Find Full Text PDFAm J Infect Control
August 2025
Dipartimento di Diagnostica e Sanità Pubblica, Università degli Studi di Verona, Verona, Italy.
Background: Textiles used in healthcare settings can act as reservoirs for microbial contamination. However, their potential role in the transmission of healthcare-associated infections (HAIs) remains underexplored.
Methods: This scoping review mapped existing evidence on the composition and management of hospital textiles in relation to HAI prevention.
Astrobiology
August 2025
International Centre for Terrestrial Antarctic Research, Te Whare Wānanga o Waikato-University of Waikato, Hamilton, New Zealand.
The McMurdo Dry Valleys may harbor diverse surface microbial communities, yet little is known about subsurface microorganisms in permafrost and their potential for paleoecological reconstruction. Here, we present microbial diversity and paleoecology from lower Wright Valley (7000- to 25,000-year-old) and Pearse Valley (>180,000-year-old) permafrost habitats in the McMurdo Dry Valleys. Using a new decontamination protocol, low-biomass extraction approaches, and 16S ribosomal RNA gene amplification sequencing, we assessed microbial community structure and diversity.
View Article and Find Full Text PDFBioact Mater
December 2025
Leibniz Universität Hannover, Institute of Physical Chemistry and Electrochemistry, Callinstr. 3a, 30167, Hannover, Germany.
Polydimethylsiloxane (PDMS) is widely used in biomedical applications due to its biocompatibility, chemical stability, flexibility, and resistance to degradation in physiological environments. However, its intrinsic inertness limits further (bio)functionalization, and its hydrophobic recovery compromises the longevity of conventional surface modifications. To address these challenges, we developed a nanoprecipitation method for the straightforward colloidal deposition, covalent thermal crosslinking, and surface anchoring of a chemically tunable, biocompatible polyacrylamide with reactive hydroxyl groups, enabling further surface modifications.
View Article and Find Full Text PDFAntimicrob Resist Infect Control
July 2025
Division of Infectious Diseases, Department of Internal Medicine, Korea University Anam Hospital, Korea University College of Medicine, 73, Goryeodae-ro, Seoul, 02841, Republic of Korea.
Background: This study evaluates the efficacy of dry-fogged hydrogen peroxide (dHP) as an "untact" room disinfection automation system (URDAS) for rapid terminal room decontamination.
Methods: This prospective study was conducted at a university-affiliated hospital in Korea. After patient discharge, dHP technology was used to decontaminate single rooms.