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Research examining restricted and repetitive patterns of behavior or interests (RRB) in autism spectrum disorder (ASD) has increased our understanding of its contribution to diagnosis and its role in development. Advances in our knowledge of RRB are hindered by the inconsistencies in how RRB is measured. The present study examined the factor structure of the Repetitive Behavior Scale-Revised (RBS-R) in a sample of 350 children with ASD ages 2-9. Confirmatory factor analysis designed for items with categorical response types was implemented to examine six proposed structural models. The five-factor model demonstrated the most parsimonious fit based on common overall fit indices that was further supported by examination of local model fit indicators, though, the four- and six-factor models evidenced adequate-to-good fit as well. Examination of RRB factor score approaches indicated only minor differences between summed item subscale scores and extracted factor scores with regard to associations with diagnostic measures. All RRB subtypes demonstrated significant associations with cognitive functioning and adaptive behavior. Implications for future research validating the RBS-R as a more extensive clinical measure of RRB in ASD are discussed. Autism Res 2019, 12: 1399-1410. © 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Repetitive behaviors are one of the two main symptoms of autism spectrum disorder (ASD). To better understand the role of repetitive behaviors, we must establish effective ways of measuring them. This study assessed the measurement qualities of the Repetitive Behavior Scale-Revised (RBS-R) in a sample of 350 children with ASD ages 2-9. We found that the RBS-R measures multiple types of repetitive behaviors and that these behaviors are related to thinking ability and independence.
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http://dx.doi.org/10.1002/aur.2159 | DOI Listing |
Trends Cogn Sci
September 2025
Sorbonne Université, CNRS, Inserm, Institut de Biologie Paris-Seine, IBPS, F-75005 Paris, France; Sorbonne Université, CNRS, Inserm, Centre de Neuroscience Neuro-SU, F-75005 Paris, France. Electronic address:
Social insects rely on multiple communication channels. These channels have traditionally been considered innate, eliciting stereotyped responses. However, recent research has shown that cognitive modulation occurs in communication contexts long assumed to be entirely genetically encoded, thus revealing a previously unrecognized cognitive plasticity in social insect communication.
View Article and Find Full Text PDFJ Safety Res
September 2025
Department of Environmental Health Sciences, School of Public Health, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address:
Introduction: Researchers, whether working in wet-labs, dry-labs, clinical settings, or field environments, encounter various hazards. However, there has been limited study on the health and safety of academic researchers. This study aimed to investigate hazardous occupational exposures and safety among researchers in academic settings at a large U.
View Article and Find Full Text PDFElife
September 2025
Department of Psychiatry & Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, United States.
Fragile X syndrome (FXS), a leading inherited cause of intellectual disability and autism, is frequently accompanied by sleep and circadian rhythm disturbances. In this study, we comprehensively characterized these disruptions and evaluated the therapeutic potential of a circadian-based intervention in the fragile X mental retardation 1 () knockout (KO) mouse. The KO mice exhibited fragmented sleep, impaired locomotor rhythmicity, and attenuated behavioral responses to light, linked to an abnormal retinal innervation and reduction of light-evoked neuronal activation in the suprachiasmatic nucleus.
View Article and Find Full Text PDFZoo Biol
September 2025
Department of Animal Welfare Science, Brookfield Zoo Chicago, Brookfield, Illinois, USA.
Addressing the presence of stereotypies - repetitive, functionless behaviors - has been at the forefront of contemporary welfare research in zoos. Stereotypies present themselves in many different forms, dependent on the biology of a species, internal and external motivational factors, individual animals' history, and early development. In the case of giraffes, a popular and charismatic species found in zoos, stereotypies concerning the mouth and tongue - oral stereotypies - are especially prevalent.
View Article and Find Full Text PDFAm J Med Genet B Neuropsychiatr Genet
September 2025
The Central Lab, the Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, People's Republic of China.
Autism spectrum disorder (ASD) is a neurodevelopmental condition that is increasingly linked to immune dysfunction and neuroinflammation. Regulatory T cells (Tregs), which are crucial in maintaining immune homeostasis, have been implicated in the pathogenesis of ASD. However, their role in neuroimmune interactions and behavioral outcomes remains poorly understood.
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