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Pressure-sensitive touch panels can measure pressure and location (3D) information simultaneously and provide an intuitive and natural method for expressing one's intention with a higher level of controllability and interactivity. However, they have been generally realized by a simple combination of pressure and location sensor or a stylus-based interface, which limit their implementation in a wide spectrum of applications. Here, we report a first demonstration (to our knowledge) of a transparent and flexible 3D touch which can sense the 3D information in a single device with the assistance of functionally designed self-generated multiscale structures. The single 3D touch system is demonstrated to draw a complex three-dimensional structure by utilizing the pressure as a third coordinate. Furthermore, rigorous theoretical analysis is carried out to achieve the target pressure performances with successful 3D data acquisition in wireless and wearable conditions, which in turn, paves the way for future wearable devices.
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http://dx.doi.org/10.1038/s41467-019-10736-6 | DOI Listing |
Comput Biol Med
June 2025
Department of Computer Science and Engineering, College of Informatics, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul, 02841, South Korea. Electronic address:
Deep learning-based pathology nuclei segmentation algorithms have demonstrated remarkable performance. Conventional methods mostly focus on supervised learning, which requires significant manual effort to generate ground truth labels. Recently, weakly supervised learning has been extensively explored as a method for overcoming this limitation by training models with sparse annotations.
View Article and Find Full Text PDFPLoS Comput Biol
June 2024
Department of Bioengineering, McGill University, Montreal, QC, Canada.
Cell sedimentation in 3D hydrogel cultures refers to the vertical migration of cells towards the bottom of the space. Understanding this poorly examined phenomenon may allow us to design better protocols to prevent it, as well as provide insights into the mechanobiology of cancer development. We conducted a multiscale experimental and mathematical examination of 3D cancer growth in triple negative breast cancer cells.
View Article and Find Full Text PDFInt J Mol Sci
January 2023
Center of 3D Printing & Organ Manufacturing, School of Intelligent Medicine, China Medical University (CMU), No. 77 Puhe Road, Shenyang North New Area, Shenyang 110122, China.
Clinically, large diameter artery defects (diameter larger than 6 mm) can be substituted by unbiodegradable polymers, such as polytetrafluoroethylene. There are many problems in the construction of small diameter blood vessels (diameter between 1 and 3 mm) and microvessels (diameter less than 1 mm), especially in the establishment of complex vascular models with multi-scale branched networks. Throughout history, the vascularization strategies have been divided into three major groups, including self-generated capillaries from implantation, pre-constructed vascular channels, and three-dimensional (3D) printed cell-laden hydrogels.
View Article and Find Full Text PDFSci Rep
May 2020
School of Mathematics and Physics, The University of Queensland, St. Lucia, Brisbane, QLD 4072, Australia.
The collective motion of cell monolayers within a tissue is a fundamental biological process that occurs during tissue formation, wound healing, cancerous invasion, and viral infection. Experiments have shown that at the onset of migration, the motility is self-generated as a polarisation wave starting from the leading edge of the monolayer and progressively propagates into the bulk. However, it is unclear how the propagation of this motility wave is influenced by cellular properties.
View Article and Find Full Text PDFNat Commun
June 2019
Department of Mechanical Engineering, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, Korea.
Pressure-sensitive touch panels can measure pressure and location (3D) information simultaneously and provide an intuitive and natural method for expressing one's intention with a higher level of controllability and interactivity. However, they have been generally realized by a simple combination of pressure and location sensor or a stylus-based interface, which limit their implementation in a wide spectrum of applications. Here, we report a first demonstration (to our knowledge) of a transparent and flexible 3D touch which can sense the 3D information in a single device with the assistance of functionally designed self-generated multiscale structures.
View Article and Find Full Text PDF