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The complete genomic RNA sequence of a tentative new umbravirus from Patrinia scabiosaefolia, tentatively named "patrinia mild mottle virus" (PatMMoV), was determined. The genome of PatMMoV consists of 4,214 nucleotides and has a typical umbravirus genome organization with four open reading frames. BLAST searches showed that the complete nucleotide sequence of PatMMoV had the highest identity (72%; 50% query coverage) to Ixeridium yellow mottle-associated virus 2 (IxYMaV-2; an unclassified umbravirus). In addition, phylogenetic analysis and pairwise comparisons showed that PatMMoV and IxYMaV-2 were the most closely related and placed in the same clade within a group of umbraviruses. These results suggest that PatMMoV is a putative new member of the genus Umbravirus in the family Tombusviridae.
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http://dx.doi.org/10.1007/s00705-019-04312-y | DOI Listing |
Sci Prog
September 2025
Xiamen Eye Center and Eye Institute of Xiamen University, School of Medicine, Xiamen, China.
BackgroundGlaucoma is recognized as the second-leading cause of complete blindness in developed countries and a significant contributor to irreversible vision loss worldwide. Understanding the potential genetic links between neurodegenerative diseases, such as Parkinson's disease, and glaucoma is crucial for developing preventive strategies.MethodsThis study utilized data from Genome-Wide Association Studies databases, focusing on European populations without gender restrictions.
View Article and Find Full Text PDFComput Biol Chem
August 2025
Department of Veterinary Tropical Diseases, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa.
As an obligate intracellular parasite, Theileria parva is strictly dependent on its host for nutrient acquisition. Transport proteins are expected to play a crucial role in the influx of essential nutrients to sustain the parasite's rapid growth. Unfortunately, the T.
View Article and Find Full Text PDFSci Rep
September 2025
Department of Pharmaceutical Sciences, Division of Pharmacognosy, University of Vienna, Vienna, 1090, Austria.
Streptomyces bambergiensis AC-800 is known as a producer of moenomycin family antibiotics active against gram-positive bacteria. Complete genome sequencing of S. bambergiensis revealed 3 replicons represented by the linear chromosome (7,652,101 bp) and two linear plasmids, pSB1 (418,507 bp) and pSB2 (81,486 bp).
View Article and Find Full Text PDFJ Vet Diagn Invest
August 2025
Clinic for Ruminants and Swine, University Leipzig, Leipzig, Germany.
In 2008, nearly 50% of weaned piglets at a German 2-site production unit in Saxony-Anhalt had skin lesions 1-2 wk after relocation into the nursery. First clinical signs were maculae, followed by papules, pustules, and finally crusts, distributed over the dorsal and lateral body flank. Tentative clinical diagnosis was an infection with swinepox virus (SWPV; family , taxon species ).
View Article and Find Full Text PDFBMC Vet Res
July 2025
Department of Internal Medicine and Infectious Diseases (Infectious Diseases), Faculty of Veterinary Medicine, Cairo University, Giza, 12211, Egypt.
Background: Data on the epidemiology and molecular characterization of feline immunodeficiency virus (FIV) in Egypt are limited. This study aimed to estimate FIV prevalence in 240 Egyptian cats during 2022–2024 using three diagnostic techniques: two point-of-care antibody detection kits (Anigen and SNAP) and one end-point PCR targeting the gene. FIV infection is defined as positivity in at least two of the three diagnostic methods or PCR alone confirmed by sequencing, Additionally, FIV-associated clinicopathological abnormalities were assessed, and, for the first time in Egypt, circulating FIV subtypes were identified through partial sequencing and phylogenetic analysis of all gene-positive samples ( = 10), along with 4 additional gene-positive samples.
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